HitPredict

Interactor 1: SLIT2 (O94813)
Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product]
Gene: SLIT2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1529 Hs			1 768
+	Hs
		1047536 NOTC2_HUMAN (1207-1524): 1.57e-37: 157: 18.44		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		857450 NOTC1_HUMAN (1249-1526): 8.4e-37: 154: 19.64		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1008016 JAG1_HUMAN (1237-1529): 6.48e-35: 148: 14.94		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114680 JAG2_HUMAN (1214-1529): 5.82e-29: 128: 15.41		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114643 NOTC3_HUMAN (846-1161): 3.56e-25: 116: 18.16		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113101 FAT1_HUMAN (859-996): 7.34e-24: 112: 26.81		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		270502 SLIT1_HUMAN (1369-1529): 5.14e-23: 109: 17.13		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113293 CRUM2_HUMAN (1416-1524): 1.3e-09: 65.2: 20.91		CUL3_HUMAN (1-768): 0: 943: 100.00