HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: SRS11 (Q05519)
Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)
Gene: SRSF11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28065597
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 484
+	Hs
		338769 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TITIN_HUMAN (33-483): 2.57e-10: 65.4: 8.99
+	Hs
		337875 EGFR_HUMAN (1-1210): 0: 1241: 100.00		MUC1_HUMAN (8-483): 3.11e-09: 61.5: 7.85
+	Hs
		338292 EGFR_HUMAN (1-1210): 0: 1241: 100.00		ANK2_HUMAN (209-479): 7.77e-09: 60.7: 19.57
+	Hs
		383566 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		NFH_HUMAN (99-484): 6.97e-22: 101: 12.95
+	Hs
		554307 ERBB4_HUMAN (1-1199): 0: 1137: 49.46		MUC1_HUMAN (8-483): 3.11e-09: 61.5: 7.85
+	Hs
		383583 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		MUC1_HUMAN (8-483): 3.11e-09: 61.5: 7.85
+	Hs
		554266 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		MUC1_HUMAN (8-483): 3.11e-09: 61.5: 7.85
+	Hs
		665581 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		ANK2_HUMAN (209-479): 7.77e-09: 60.7: 19.57
+	Hs
		554283 ZAP70_HUMAN (718-961): 5.57e-53: 199: 39.59		MUC1_HUMAN (8-483): 3.11e-09: 61.5: 7.85