Interactor 1: IL33 (O95760)
Interleukin-33 (IL-33) (Interleukin-1 family member 11) (IL-1F11) (Nuclear factor from high endothelial venules) (NF-HEV) [Cleaved into: Interleukin-33 (95-270); Interleukin-33 (99-270); Interleukin-33 (109-270)]
Gene: IL33

Interactor 2: IL1AP (Q9NPH3)
Interleukin-1 receptor accessory protein (IL-1 receptor accessory protein) (IL-1RAcP) (EC 3.2.2.6) (Interleukin-1 receptor 3) (IL-1R-3) (IL-1R3)
Gene: IL1RAP

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 19836339
Identification Methods isothermal titration calorimetry, nuclear magnetic resonance
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0032736 - positive regulation of interleukin-13 production
GO:0032753 - positive regulation of interleukin-4 production
GO:0032754 - positive regulation of interleukin-5 production
GO:0032755 - positive regulation of interleukin-6 production
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 270
Hs

1 570
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024