Interactor 1: NFAT5 (O94916)
Nuclear factor of activated T-cells 5 (NF-AT5) (T-cell transcription factor NFAT5) (Tonicity-responsive enhancer-binding protein) (TonE-binding protein) (TonEBP)
Gene: NFAT5

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 37429858
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006974 - DNA damage response
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1531
Hs

1 522
+ Hs
+ Hs
+ Hs
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+ Hs

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Last updated: 11Aug2025