HitPredict

Interactor 1: BAG3 (O95817)
BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1)
Gene: BAG3

Interactor 2: Q96BE0 (Q96BE0)
Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)
Gene: Q96BE0

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BAG~HSP70
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 575 Hs			1 269
+	Hs
		324256 BAG3_HUMAN (1-575): 0: 809: 100.00		HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58
+	Hs
		324195 BAG3_HUMAN (1-575): 0: 809: 100.00		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		324561 BAG3_HUMAN (1-575): 0: 809: 100.00		Q96IS6_HUMAN (1-269): 3.32e-130: 382: 100.00
+	Hs
		324190 BAG3_HUMAN (1-575): 0: 809: 100.00		HS71A_HUMAN (1-269): 2.24e-126: 374: 78.44
+	Hs
		324298 BAG3_HUMAN (1-575): 0: 809: 100.00		HSP72_HUMAN (1-269): 1.82e-126: 374: 78.07
+	Hs
		324216 BAG3_HUMAN (1-575): 0: 809: 100.00		HSP76_HUMAN (1-269): 5.75e-126: 373: 69.15
+	Hs
		324435 BAG3_HUMAN (1-575): 0: 809: 100.00		Q53FC7_HUMAN (1-269): 5.5e-126: 373: 68.77
+	Hs
		72231 BAG3_HUMAN (1-575): 0: 809: 100.00		B3KTT5_HUMAN (1-269): 3.06e-126: 368: 78.07
+	Mm
		926166 BAG3_MOUSE (1-575): 0: 762: 83.31		HSP7C_MOUSE (1-269): 1.33e-130: 385: 99.63
+	Mm
		571868 BAG3_MOUSE (1-575): 0: 762: 83.31		HS71B_MOUSE (1-269): 4.29e-130: 384: 77.70
+	Mm
		571864 BAG4_MOUSE (381-499): 1.39e-37: 146: 43.70		HS71B_MOUSE (1-269): 4.29e-130: 384: 77.70
+	Hs
		314010 BAG4_HUMAN (381-499): 3.45e-33: 134: 43.70		HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58
+	Hs
		313996 BAG4_HUMAN (381-499): 3.45e-33: 134: 43.70		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		314025 BAG4_HUMAN (381-499): 3.45e-33: 134: 43.70		HSP72_HUMAN (1-269): 1.82e-126: 374: 78.07
+	Hs
		314001 BAG4_HUMAN (381-499): 3.45e-33: 134: 43.70		HSP76_HUMAN (1-269): 5.75e-126: 373: 69.15
+	Hs
		314060 BAG4_HUMAN (381-499): 3.45e-33: 134: 43.70		Q53FC7_HUMAN (1-269): 5.5e-126: 373: 68.77
+	Hs
		72230 BAG4_HUMAN (381-499): 3.45e-33: 134: 43.70		B3KTT5_HUMAN (1-269): 3.06e-126: 368: 78.07
+	Dm
		505107 Q9VU81_DROME (398-498): 1.2e-26: 116: 32.11		HSP7D_DROME (1-235): 1.12e-128: 380: 82.55
+	Dm
		65601 A8JNS4_DROME (398-498): 1.33e-26: 116: 32.11		HSP7D_DROME (1-235): 1.12e-128: 380: 82.55
+	Hs
		314113 BAG4_HUMAN (381-499): 3.45e-33: 134: 43.70		Q96BE0_HUMAN (1-269): 3.21e-125: 358: 100.00