HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: MOB3C (Q70IA8)
MOB kinase activator 3C (Mob1 homolog 2C) (Mps one binder kinase activator-like 2C)
Gene: MOB3C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19739119
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 216
+	Hs
		325791 LATS1_HUMAN (1-1130): 0: 934: 100.00		MOB3B_HUMAN (1-216): 4.23e-116: 331: 71.76
+	Hs
		325844 LATS1_HUMAN (1-1130): 0: 934: 100.00		MOB3A_HUMAN (5-216): 1.49e-112: 322: 74.06
+	Hs
		325891 LATS1_HUMAN (1-1130): 0: 934: 100.00		MOB1A_HUMAN (13-214): 2.75e-107: 308: 52.48
+	Hs
		325787 LATS1_HUMAN (1-1130): 0: 934: 100.00		MOB1B_HUMAN (13-214): 2.54e-106: 306: 50.50
+	Hs
		325784 LATS1_HUMAN (1-1130): 0: 934: 100.00		MOB2_HUMAN (12-215): 1.86e-74: 226: 32.52
+	Hs
		325949 LATS1_HUMAN (1-1130): 0: 934: 100.00		PHOCN_HUMAN (10-204): 3.73e-67: 207: 18.18
+	Hs
		1198336 LATS2_HUMAN (13-1121): 0: 751: 49.61		MOB3B_HUMAN (1-216): 4.23e-116: 331: 71.76
+	Hs
		1174306 LATS2_HUMAN (13-1121): 0: 751: 49.61		MOB3C_HUMAN (1-216): 1.99e-115: 329: 100.00
+	Hs
		1285989 LATS2_HUMAN (13-1121): 0: 751: 49.61		MOB3A_HUMAN (5-216): 1.49e-112: 322: 74.06
+	Hs
		1333705 LATS2_HUMAN (13-1121): 0: 751: 49.61		MOB1A_HUMAN (13-214): 2.75e-107: 308: 52.48
+	Hs
		1185503 LATS2_HUMAN (13-1121): 0: 751: 49.61		MOB1B_HUMAN (13-214): 2.54e-106: 306: 50.50
+	Hs
		1344983 LATS2_HUMAN (13-1121): 0: 751: 49.61		PHOCN_HUMAN (10-204): 3.73e-67: 207: 18.18
+	Hs
		1333714 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		MOB1A_HUMAN (13-214): 2.75e-107: 308: 52.48
+	Hs
		1185506 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		MOB1B_HUMAN (13-214): 2.54e-106: 306: 50.50
+	Sc
		774485 CBK1_YEAST (397-1091): 2.99e-167: 514: 30.07		MOB1_YEAST (10-214): 2.96e-86: 259: 36.89
+	Ca
		1124241 CBK1_CANAL (448-1091): 9.16e-168: 514: 32.18		MOB2_CANAL (42-212): 9.88e-80: 242: 34.50
+	Sc
		797131 CBK1_YEAST (397-1091): 2.99e-167: 514: 30.07		MOB2_YEAST (42-213): 2.3e-74: 227: 36.63
+	Sp
		140739 ORB6_SCHPO (630-1086): 3.84e-167: 503: 39.39		MOB2_SCHPO (26-214): 1.87e-75: 229: 33.33
+	Hs
		1174241 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		MOB2_HUMAN (12-215): 1.86e-74: 226: 32.52
+	Hs
		1069621 STK38_HUMAN (622-1089): 5.96e-165: 497: 40.17		MOB2_HUMAN (12-215): 1.86e-74: 226: 32.52