Protein: PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B)

Gene: PDE3B
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q13370

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0004114 - 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity
GO:0004119 - cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1032771

PDE3A
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

1

8

High-throughput

0.691

High

771184

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.679

High

1032793

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

3

1

High-throughput

0.667

High

1032829

TX264
Testis-expressed protein 264

3

0

High-throughput

0.638

High

1032785

LRRT1
Leucine-rich repeat transmembrane neuronal protein 1

2

4

High-throughput

0.628

High

1032801

KCNS3
Potassium voltage-gated channel subfamily S member 3

2

3

High-throughput

0.628

High

1032792

LNX1
E3 ubiquitin-protein ligase LNX

2

2

High-throughput

0.606

High

180592

TEX28
Testis-specific protein TEX28

2

0

High-throughput

0.602

High

884411

TMPS3
Transmembrane protease serine 3

2

0

High-throughput

0.602

High

1032797

RN170
E3 ubiquitin-protein ligase RNF170

2

0

High-throughput

0.602

High

313174

RPGF3
Rap guanine nucleotide exchange factor 3

1

2

Small-scale

0.597

High

240494

HPGDS
Hematopoietic prostaglandin D synthase

2

0

High-throughput

0.580

High

977410

KCNC4
Potassium voltage-gated channel subfamily C member 4

2

3

High-throughput

0.574

High

1032789

I17RC
Interleukin-17 receptor C

2

1

High-throughput

0.574

High

1032827

PCDC2
Protocadherin alpha-C2

2

1

High-throughput

0.574

High

1032777

PI3R6
Phosphoinositide 3-kinase regulatory subunit 6

1

0

Small-scale

0.561

High

890136

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

1032774

EREP1
Endosomal transmembrane epsin interactor 1

2

1

High-throughput

0.558

High

940414

CXAR
Coxsackievirus and adenovirus receptor

1

1

High-throughput

0.553

High

354946

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

2

1

High-throughput

0.552

High

253890

LRP3
Low-density lipoprotein receptor-related protein 3

1

1

High-throughput

0.536

High

513739

CP19A
Aromatase

1

1

High-throughput

0.536

High

681827

AKT1
RAC-alpha serine/threonine-protein kinase

1

9

High-throughput

0.536

High

945196

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

1

High-throughput

0.536

High

946383

EREP3
Protein ENTREP3

1

1

High-throughput

0.536

High

1015972

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

5

High-throughput

0.536

High

1032796

ZDH12
Palmitoyltransferase ZDHHC12

1

2

High-throughput

0.536

High

1032802

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

1

High-throughput

0.536

High

1032824

AKT3
RAC-gamma serine/threonine-protein kinase

1

5

High-throughput

0.536

High

452412

PGFRB
Platelet-derived growth factor receptor beta

1

0

High-throughput

0.513

High

1032772

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

1032775

AMHR2
Anti-Muellerian hormone type-2 receptor

1

0

High-throughput

0.513

High

1032776

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1032809

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1032816

TLR9
Toll-like receptor 9

1

0

High-throughput

0.513

High

1032823

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

0

High-throughput

0.513

High

558722

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

3

High-throughput

0.489

High

1032804

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

2

High-throughput

0.489

High

1032826

PCDGL
Protocadherin gamma-C4

1

1

High-throughput

0.489

High

822541

PK3CG
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

1

0

Small-scale

0.479

High

436286

RHOC
Rho-related GTP-binding protein RhoC

1

11

High-throughput

0.479

High

545353

RAC2
Ras-related C3 botulinum toxin substrate 2

1

11

High-throughput

0.479

High

838809

EMD
Emerin

1

1

High-throughput

0.479

High

845463

RAB9A
Ras-related protein Rab-9A

1

2

High-throughput

0.479

High

883899

NAC3
Sodium/calcium exchanger 3

1

1

High-throughput

0.479

High

893966

CDC42
Cell division control protein 42 homolog

1

12

High-throughput

0.479

High

900437

RHOA
Transforming protein RhoA

1

11

High-throughput

0.479

High

904523

1433G
14-3-3 protein gamma

1

18

High-throughput

0.479

High

909520

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.479

High

927008

1433Z
14-3-3 protein zeta/delta

1

18

High-throughput

0.479

High

950967

RHOG
Rho-related GTP-binding protein RhoG

1

11

High-throughput

0.479

High

961647

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.479

High

981979

1433F
14-3-3 protein eta

1

18

High-throughput

0.479

High

990432

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.479

High

1032770

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

7

High-throughput

0.479

High

1032778

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.479

High

1032779

RNF43
E3 ubiquitin-protein ligase RNF43

1

1

High-throughput

0.479

High

1032783

SYNE3
Nesprin-3

1

2

High-throughput

0.479

High

1032790

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1032794

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

1032798

DNJC1
DnaJ homolog subfamily C member 1

1

3

High-throughput

0.479

High

1032800

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

1032820

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1032822

SEC63
Translocation protein SEC63 homolog

1

2

High-throughput

0.479

High

48016

TM129
E3 ubiquitin-protein ligase TM129

1

0

High-throughput

0.458

High

163800

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

273785

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

390210

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

390863

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

573680

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

785900

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

795117

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

825404

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

847459

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

885922

EVA1C
Protein eva-1 homolog C

1

0

High-throughput

0.458

High

926678

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

0

High-throughput

0.458

High

1032769

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1032773

RAB35
Ras-related protein Rab-35

1

0

High-throughput

0.458

High

1032780

S39A4
Zinc transporter ZIP4

1

0

High-throughput

0.458

High

1032786

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

1032787

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1032791

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.458

High

1032799

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1032803

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1032806

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1032811

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1032812

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1032815

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1032817

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

1032828

SRPRB
Signal recognition particle receptor subunit beta

1

0

High-throughput

0.458

High

200343

LRRT2
Leucine-rich repeat transmembrane neuronal protein 2

1

4

High-throughput

0.437

High

831883

CEBPD
CCAAT/enhancer-binding protein delta

1

1

Small-scale

0.437

High

1032782

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1032807

DJC25
DnaJ homolog subfamily C member 25

1

2

High-throughput

0.437

High

1032808

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.437

High

1032810

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

646867

1433T
14-3-3 protein theta

1

18

Small-scale

0.408

High

1032813

ANRA2
Ankyrin repeat family A protein 2

1

0

Small-scale

0.391

High

1032781

LRC8B
Volume-regulated anion channel subunit LRRC8B

2

0

High-throughput

0.328

High

1032819

MARH4
E3 ubiquitin-protein ligase MARCHF4

2

0

High-throughput

0.318

High

1032821

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

2

0

High-throughput

0.318

High

1018890

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

0

High-throughput

0.279

Low

1032768

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

0

High-throughput

0.279

Low

1032784

CLC14
C-type lectin domain family 14 member A

1

0

High-throughput

0.279

Low

1032795

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1032814

KCMB3
Calcium-activated potassium channel subunit beta-3

1

0

High-throughput

0.279

Low

514683

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.249

Low

963943

IL9R
Interleukin-9 receptor

1

0

High-throughput

0.249

Low

1032788

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

1032805

TMM59
Transmembrane protein 59

1

0

High-throughput

0.249

Low

1032818

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1032825

DJC16
DnaJ homolog subfamily C member 16

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024