HitPredict

Interactor 1: GPAN1 (O95872)
G patch domain and ankyrin repeat-containing protein 1 (Ankyrin repeat domain-containing protein 59) (G patch domain-containing protein 10) (HLA-B-associated transcript 4) (Protein G5)
Gene: GPANK1

Interactor 2: AP1B1 (Q10567)
AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)
Gene: AP1B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 356 Hs			1 949
+	Hs
		327057 GPAN1_HUMAN (1-356): 8.87e-103: 308: 100.00		AP2B1_HUMAN (1-949): 0: 944: 81.45
+	Hs
		926051 KDIS_HUMAN (45-282): 2.89e-40: 153: 16.39		AP2B1_HUMAN (1-949): 0: 944: 81.45
+	Hs
		166905 ANR28_HUMAN (33-322): 1.04e-30: 125: 13.96		AP2B1_HUMAN (1-949): 0: 944: 81.45
+	Hs
		925941 ANKH1_HUMAN (37-294): 5.29e-29: 120: 13.48		AP2B1_HUMAN (1-949): 0: 944: 81.45
+	Hs
		166867 ANR28_HUMAN (33-322): 1.04e-30: 125: 13.96		AP2A2_HUMAN (12-945): 0: 625: 18.33
+	Hs
		119955 ANK3_HUMAN (26-231): 8.51e-38: 146: 13.59		AP3B1_HUMAN (6-620): 6.51e-156: 489: 27.73