HitPredict

Interactor 1: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Interactor 2: ERGI3 (Q9Y282)
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (Serologically defined breast cancer antigen NY-BR-84)
Gene: ERGIC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.50	0.607

Property	Details
Experiments	33961781, 36949045, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 116 Hs			1 383
+	Hs
		662368 VAMP1_HUMAN (2-78): 7.05e-26: 95: 36.36		ERGI3_HUMAN (1-383): 0: 564: 100.00
+	Hs
		278582 VAMP4_HUMAN (3-73): 1.95e-25: 94.6: 29.58		ERGI3_HUMAN (1-383): 0: 564: 100.00
+	Hs
		989401 VAMP2_HUMAN (2-75): 3.53e-25: 93: 39.19		ERGI3_HUMAN (1-383): 0: 564: 100.00
+	Hs
		1154787 VAMP3_HUMAN (2-72): 1.48e-24: 91.1: 38.03		ERGI3_HUMAN (1-383): 0: 564: 100.00
+	Hs
		328724 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		ERGI2_HUMAN (2-380): 6.56e-117: 346: 32.19
+	Hs
		278548 VAMP4_HUMAN (3-73): 1.95e-25: 94.6: 29.58		ERGI2_HUMAN (2-380): 6.56e-117: 346: 32.19
+	Zm
		31406 A0A1D6KH00_MAIZE (5-91): 6.21e-33: 122: 28.74		Q5EUD1_MAIZE (1-141): 2.05e-35: 137: 28.87
+	Hs
		989368 VAMP2_HUMAN (2-75): 3.53e-25: 93: 39.19		ERGI1_HUMAN (7-109): 6.37e-27: 110: 34.91
+	Hs
		1154702 VAMP3_HUMAN (2-72): 1.48e-24: 91.1: 38.03		ERGI1_HUMAN (7-109): 6.37e-27: 110: 34.91