HitPredict

Interactor 1: TOM40 (O96008)
Mitochondrial import receptor subunit TOM40 homolog (Protein Haymaker) (Translocase of outer membrane 40 kDa subunit homolog) (p38.5)
Gene: TOMM40

Interactor 2: TOM22 (Q9NS69)
Mitochondrial import receptor subunit TOM22 homolog (hTom22) (1C9-2) (Translocase of outer membrane 22 kDa subunit homolog)
Gene: TOMM22

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.924

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 17635912, 22280891, 15644312
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Porin_3~Tom22
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0005742 - mitochondrial outer membrane translocase complex GO:0006626 - protein targeting to mitochondrion GO:0008320 - protein transmembrane transporter activity and 3 others more... GO:0016020 - membrane GO:0045040 - protein insertion into mitochondrial outer membrane GO:0140596 - TOM complex
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	361
Hs

1	142

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024