HitPredict

Interactor 1: PAK4 (O96013)
Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)
Gene: PAK4

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 591 Hs			1 1278
+	Hs
		1051364 DCLK2_HUMAN (31-591): 2.1e-132: 406: 17.65		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		331091 PAK4_HUMAN (1-591): 0: 586: 100.00		KI13B_HUMAN (14-145): 4.98e-32: 138: 32.85
+	Hs
		522546 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH1_HUMAN (374-1278): 2.47e-39: 162: 10.82
+	Hs
		522545 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH1_HUMAN (374-1278): 2.47e-39: 162: 10.82
+	Hs
		682199 AKT2_HUMAN (261-583): 1.6e-127: 384: 22.94		CLIP3_HUMAN (10-139): 7.2e-31: 131: 31.34
+	Hs
		1051494 STK26_HUMAN (315-574): 2.21e-52: 186: 38.31		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		522610 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH7_HUMAN (64-763): 2.65e-27: 122: 9.80
+	Hs
		522609 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH7_HUMAN (64-763): 2.65e-27: 122: 9.80
+	Hs
		528371 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH6_HUMAN (47-712): 5.82e-26: 118: 9.71
+	Hs
		528369 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH6_HUMAN (47-712): 5.82e-26: 118: 9.71
+	Hs
		1027453 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH13_HUMAN (637-1278): 2.11e-21: 103: 10.87
+	Hs
		1023138 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH13_HUMAN (637-1278): 2.11e-21: 103: 10.87
+	Hs
		675140 KS6A3_HUMAN (265-591): 5.2e-113: 355: 24.27		CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32
+	Hs
		1027452 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH2_HUMAN (830-1278): 9.73e-15: 81.8: 8.67
+	Hs
		1023137 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH2_HUMAN (830-1278): 9.73e-15: 81.8: 8.67
+	Hs
		502912 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH3_HUMAN (830-1278): 8.46e-13: 75.6: 10.11
+	Hs
		502911 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH3_HUMAN (830-1278): 8.46e-13: 75.6: 10.11
+	Hs
		528409 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH8_HUMAN (62-436): 3.47e-11: 70.2: 11.05
+	Hs
		528408 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH8_HUMAN (62-436): 3.47e-11: 70.2: 11.05
+	Hs
		1026211 PAK1_HUMAN (3-210): 7.55e-29: 122: 19.62		TBCB_HUMAN (19-96): 2.34e-32: 128: 46.91