HitPredict

Interactor 1: APBA3 (O96018)
Amyloid-beta A4 precursor protein-binding family A member 3 (Adapter protein X11gamma) (Neuron-specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3)
Gene: APBA3

Interactor 2: NECA3 (Q96P71)
N-terminal EF-hand calcium-binding protein 3 (Amyloid-beta A4 protein-binding family A member 2-binding protein) (Nek2-interacting protein 1) (Neuronal calcium-binding protein 3) (X11L-binding protein 51)
Gene: NECAB3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	28514442, 33961781, 26948053
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 575 Hs			1 396
+	Hs
		1299153 APBA2_HUMAN (92-575): 2.54e-106: 338: 50.10		NECA3_HUMAN (1-396): 0: 642: 100.00
+	Hs
		132920 SDCB1_HUMAN (387-572): 1.63e-53: 185: 24.47		NECA2_HUMAN (2-390): 0: 537: 37.06
+	Hs
		1191765 INADL_HUMAN (375-555): 3.27e-14: 78.3: 18.10		NECA2_HUMAN (2-390): 0: 537: 37.06