HitPredict

Interactor 1: O96692 (O96692)
RE63021p (Ras-associated protein 2-like, isoform A) (Ras-related protein 2-like protein)
Gene: Rap2l

Interactor 2: RGS (Q9VCX1)
Regulator of G-protein signaling loco (RGS) (Locomotion defects protein) (Loco)
Gene: loco

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	15710747
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PDZ~Ras, RBD~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 182 Dm			1 1541
+	Dm
		442972 RAP1_DROME (1-165): 9.67e-66: 201: 58.18		RGS_DROME (1-1541): 0: 1824: 100.00
+	Dm
		443010 RAS1_DROME (1-174): 1.59e-44: 147: 42.53		RGS_DROME (1-1541): 0: 1824: 100.00
+	Dm
		332221 O96692_DROME (16-182): 7.37e-86: 252: 100.00		Q9VCX2_DROME (711-1541): 0: 973: 99.64
+	Dm
		442973 RAP1_DROME (1-165): 9.67e-66: 201: 58.18		Q9VCX2_DROME (711-1541): 0: 973: 99.64
+	Dm
		443011 RAS1_DROME (1-174): 1.59e-44: 147: 42.53		Q9VCX2_DROME (711-1541): 0: 973: 99.64
+	Mm
		867148 RAB2A_MOUSE (4-170): 2.72e-76: 228: 33.93		RGS14_MOUSE (813-1293): 6.55e-165: 510: 30.88
+	Mm
		918978 RAB1A_MOUSE (4-176): 6.77e-75: 224: 33.33		RGS14_MOUSE (813-1293): 6.55e-165: 510: 30.88
+	Hs
		207508 RAP2A_HUMAN (1-178): 2.19e-71: 215: 69.66		RGS14_HUMAN (813-1293): 2.69e-166: 514: 30.33
+	Hs
		207516 RAP1A_HUMAN (1-165): 1.31e-68: 208: 60.24		RGS14_HUMAN (813-1293): 2.69e-166: 514: 30.33
+	Rn
		139848 RASN_RAT (1-174): 9.84e-45: 147: 47.13		RGS12_RAT (70-516): 2.41e-148: 492: 31.34
+	Hs
		207624 RB11A_HUMAN (4-176): 6.88e-73: 220: 32.76		AKA10_HUMAN (596-978): 6.7e-84: 291: 15.92
+	Hs
		782023 RAP1B_HUMAN (1-182): 4.11e-78: 232: 56.52		RGS2_HUMAN (755-947): 5.99e-61: 209: 26.29
+	Hs
		782022 RAB2A_HUMAN (4-170): 4.26e-76: 228: 33.93		RGS2_HUMAN (755-947): 5.99e-61: 209: 26.29