Protein: STA5A
Signal transducer and activator of transcription 5A

Gene: STA5A, STAT5A
Organism: Homo sapiens
Interactions: 112
UniProt ID: P42229

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

338073

EGFR
Epidermal growth factor receptor

6

20

Small-scale

0.946

High

786594

STA5B
Signal transducer and activator of transcription 5B

4

16

Small-scale

0.895

High

238379

JAK2
Tyrosine-protein kinase JAK2

4

20

Small-scale

0.888

High

786590

CRKL
Crk-like protein

3

4

Small-scale

0.870

High

581154

EPOR
Erythropoietin receptor

3

20

Small-scale

0.861

High

786612

ERBB4
Receptor tyrosine-protein kinase erbB-4

3

20

Small-scale

0.827

High

237478

TLR2
Toll-like receptor 2

2

2

High-throughput

0.811

High

786601

PTN11
Tyrosine-protein phosphatase non-receptor type 11

2

17

Small-scale

0.789

High

573605

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

17

Small-scale

0.771

High

786602

BTK
Tyrosine-protein kinase BTK

1

15

Small-scale

0.761

High

786595

JAK3
Tyrosine-protein kinase JAK3

2

20

Small-scale

0.757

High

786637

CISH
Cytokine-inducible SH2-containing protein

2

20

Small-scale

0.754

High

616757

JAK1
Tyrosine-protein kinase JAK1

1

20

Small-scale

0.740

High

786587

STA5A
Signal transducer and activator of transcription 5A

1

16

High-throughput

0.698

High

337381

ABL1
Tyrosine-protein kinase ABL1

1

14

Small-scale

0.692

High

610278

CBL
E3 ubiquitin-protein ligase CBL

4

3

Small-scale

0.680

High

440394

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

3

2

High-throughput

0.675

High

505785

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

3

1

High-throughput

0.675

High

786603

EP300
Histone acetyltransferase p300

3

13

Small-scale

0.669

High

540452

IL2RB
Interleukin-2 receptor subunit beta

3

20

Small-scale

0.651

High

786610

PDK2
[Pyruvate dehydrogenase

2

2

High-throughput

0.628

High

786620

KLHL7
Kelch-like protein 7

2

1

High-throughput

0.628

High

658829

MK01
Mitogen-activated protein kinase 1

2

5

Small-scale

0.624

High

369132

ESR1
Estrogen receptor

2

20

Small-scale

0.621

High

146672

SOCS7
Suppressor of cytokine signaling 7

1

18

Small-scale

0.618

High

452369

PGFRB
Platelet-derived growth factor receptor beta

1

14

Small-scale

0.618

High

499239

KIT
Mast/stem cell growth factor receptor Kit

1

13

Small-scale

0.618

High

562533

IL7RA
Interleukin-7 receptor subunit alpha

1

2

High-throughput

0.618

High

601477

FGFR2
Fibroblast growth factor receptor 2

1

19

Small-scale

0.618

High

666031

SHC1
SHC-transforming protein 1

1

10

Small-scale

0.618

High

669139

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

20

Small-scale

0.618

High

776595

STAT3
Signal transducer and activator of transcription 3

1

16

Small-scale

0.618

High

786263

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

16

Small-scale

0.618

High

786625

OLIG1
Oligodendrocyte transcription factor 1

2

2

High-throughput

0.594

High

740452

PPARG
Peroxisome proliferator-activated receptor gamma

2

20

Small-scale

0.584

High

749184

BRCA1
Breast cancer type 1 susceptibility protein

2

7

Small-scale

0.584

High

126228

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

2

3

High-throughput

0.574

High

489712

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

2

3

High-throughput

0.574

High

786611

PDK3
[Pyruvate dehydrogenase

2

2

High-throughput

0.574

High

786605

NMI
N-myc-interactor

1

6

Small-scale

0.573

High

786619

CARM1
Histone-arginine methyltransferase CARM1

1

4

Small-scale

0.561

High

786633

ANM1
Protein arginine N-methyltransferase 1

1

4

Small-scale

0.561

High

362908

FINC
Fibronectin

1

1

High-throughput

0.555

High

411330

INSR
Insulin receptor

1

15

Small-scale

0.553

High

786617

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.553

High

786630

HTF4
Transcription factor 12

1

0

High-throughput

0.549

High

745084

RBMX
RNA-binding motif protein, X chromosome

1

2

High-throughput

0.541

High

786588

MAGAC
Melanoma-associated antigen 12

1

2

High-throughput

0.541

High

786626

ZN596
Zinc finger protein 596

1

2

High-throughput

0.541

High

207543

RNF13
E3 ubiquitin-protein ligase RNF13

1

2

High-throughput

0.536

High

786613

SF3A1
Splicing factor 3A subunit 1

1

1

High-throughput

0.536

High

786634

GDF15
Growth/differentiation factor 15

1

1

High-throughput

0.536

High

786641

DDX20
Probable ATP-dependent RNA helicase DDX20

1

1

High-throughput

0.536

High

786615

TET2
Methylcytosine dioxygenase TET2

1

0

High-throughput

0.529

High

786636

PRDC1
Phosphoribosyltransferase domain-containing protein 1

1

0

High-throughput

0.518

High

786631

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

3

Small-scale

0.515

High

786640

STAP2
Signal-transducing adaptor protein 2

1

1

Small-scale

0.515

High

786635

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

0

High-throughput

0.513

High

786638

ADDG
Gamma-adducin

1

0

High-throughput

0.513

High

786596

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

High-throughput

0.508

High

786627

ESR2
Estrogen receptor beta

1

19

Small-scale

0.501

High

335062

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.494

High

786644

ICAM5
Intercellular adhesion molecule 5

1

4

High-throughput

0.489

High

786629

FBXW7
F-box/WD repeat-containing protein 7

1

4

Small-scale

0.481

High

786632

EPAS1
Endothelial PAS domain-containing protein 1

1

6

High-throughput

0.481

High

353051

IL2RA
Interleukin-2 receptor subunit alpha

1

2

Small-scale

0.479

High

414460

PRGR
Progesterone receptor

1

17

Small-scale

0.479

High

486756

MYB
Transcriptional activator Myb

1

1

Small-scale

0.479

High

501012

IRF1
Interferon regulatory factor 1

1

20

Small-scale

0.479

High

540804

PO2F1
POU domain, class 2, transcription factor 1

1

6

Small-scale

0.479

High

587462

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

10

Small-scale

0.479

High

622386

CCND1
G1/S-specific cyclin-D1

1

5

Small-scale

0.479

High

673032

CCND2
G1/S-specific cyclin-D2

1

5

Small-scale

0.479

High

781319

BCL6
B-cell lymphoma 6 protein

1

2

Small-scale

0.479

High

786589

CBX5
Chromobox protein homolog 5

1

1

Small-scale

0.479

High

786591

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

786592

SMCA4
Transcription activator BRG1

1

5

Small-scale

0.479

High

786600

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

786604

CBLB
E3 ubiquitin-protein ligase CBL-B

1

3

Small-scale

0.479

High

786606

SQSTM
Sequestosome-1

1

1

Small-scale

0.479

High

786607

HDAC1
Histone deacetylase 1

1

10

Small-scale

0.479

High

786608

RUNX2
Runt-related transcription factor 2

1

1

Small-scale

0.479

High

786614

NCOA1
Nuclear receptor coactivator 1

1

10

Small-scale

0.479

High

786639

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

786642

LEF1
Lymphoid enhancer-binding factor 1

1

1

Small-scale

0.479

High

786643

TBX21
T-box transcription factor TBX21

1

6

Small-scale

0.479

High

786645

R3HD2
R3H domain-containing protein 2

1

5

High-throughput

0.479

High

786597

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.460

High

396862

IL5
Interleukin-5

1

0

Small-scale

0.458

High

786593

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

786623

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

279466

FLOT1
Flotillin-1

1

5

High-throughput

0.457

High

786609

FLOT2
Flotillin-2

1

5

High-throughput

0.457

High

786624

ANGL6
Angiopoietin-related protein 6

1

4

High-throughput

0.457

High

701707

IL3RB
Cytokine receptor common subunit beta

1

17

Small-scale

0.445

High

786628

CBP
CREB-binding protein

1

14

Small-scale

0.445

High

72713

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

1

High-throughput

0.439

High

786599

RT06
Small ribosomal subunit protein bS6m

1

1

High-throughput

0.439

High

786616

TXD11
Thioredoxin domain-containing protein 11

1

2

High-throughput

0.439

High

596511

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

1

Small-scale

0.437

High

786598

KRT83
Keratin, type II cuticular Hb3

1

0

High-throughput

0.426

High

78247

B5MCU0
R3H domain containing 2

1

5

High-throughput

0.407

High

296792

NOL4
Nucleolar protein 4

1

0

High-throughput

0.279

Low

311898

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

786618

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.279

Low

786621

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.279

Low

410643

UD2B4
UDP-glucuronosyltransferase 2B4

1

0

High-throughput

0.251

Low

514671

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.251

Low

786622

AQP11
Aquaporin-11

1

0

High-throughput

0.251

Low

546358

IL9
Interleukin-9

1

0

Small-scale

0.249

Low

560045

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024