Interactor 1: O96989 (O96989)
CDC45L (Cell division cycle 45) (EG:BACR7A4.11 protein) (LD35753p)
Gene: Cdc45

Interactor 2: MCM5 (Q9VGW6)
DNA replication licensing factor Mcm5 (EC 3.6.4.12) (Minichromosome maintenance 5 protein) (DmMCM5)
Gene: MCM5

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 11024168, 16798881, 20122406, unassigned4
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, experimental interaction detection
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC45~MCM_lid, CDC45~MCM_N, CDC45~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0006270 - DNA replication initiation
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 575
Dm

1 733
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Last updated: 15 Jul 2024