HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 243 Hs			1 618
+	Hs
		332851 VAPB_HUMAN (1-243): 2.24e-87: 260: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		332944 VAPB_HUMAN (1-243): 2.24e-87: 260: 100.00		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		332945 VAPB_HUMAN (1-243): 2.24e-87: 260: 100.00		CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54
+	Hs
		333012 VAPB_HUMAN (1-243): 2.24e-87: 260: 100.00		RAB35_HUMAN (5-168): 3.57e-76: 242: 24.70
+	Hs
		332969 VAPB_HUMAN (1-243): 2.24e-87: 260: 100.00		RHOG_HUMAN (3-170): 1.69e-74: 238: 27.47
+	Hs
		332958 VAPB_HUMAN (1-243): 2.24e-87: 260: 100.00		RAC1_HUMAN (3-181): 3.96e-74: 237: 26.43
+	Hs
		332953 VAPB_HUMAN (1-243): 2.24e-87: 260: 100.00		RB11A_HUMAN (5-202): 4.27e-72: 232: 19.00
+	Hs
		581341 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		953721 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		955694 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54
+	Hs
		988775 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RAC1_HUMAN (3-181): 3.96e-74: 237: 26.43
+	Hs
		976622 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RB11A_HUMAN (5-202): 4.27e-72: 232: 19.00
+	Hs
		956022 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RAB8A_HUMAN (5-187): 4.8e-71: 229: 17.30
+	Hs
		332948 VAPB_HUMAN (1-243): 2.24e-87: 260: 100.00		RHOA_HUMAN (6-168): 1.75e-11: 65.5: 28.25
+	Hs
		333209 VAPB_HUMAN (1-243): 2.24e-87: 260: 100.00		RHOF_HUMAN (2-167): 3.39e-11: 65.1: 26.67
+	Hs
		332832 VAPB_HUMAN (1-243): 2.24e-87: 260: 100.00		RHOC_HUMAN (6-168): 3.88e-11: 64.3: 28.25
+	Hs
		126415 VAPB_HUMAN (1-243): 2.24e-87: 260: 100.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		962576 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RHOA_HUMAN (6-168): 1.75e-11: 65.5: 28.25
+	Hs
		466502 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RHOC_HUMAN (6-168): 3.88e-11: 64.3: 28.25
+	Hs
		126844 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89