Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: SPTA1 (P02549)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 9593709
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH3_1, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0015629 - actin cytoskeleton
GO:0030036 - actin cytoskeleton organization
GO:0051015 - actin filament binding
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1130
Hs

1 2419
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024