Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: PAXI (P49023)
Paxillin
Gene: PXN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 15657067
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007165 - signal transduction
GO:0019903 - protein phosphatase binding
GO:0034614 - cellular response to reactive oxygen species
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 591
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024