HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: RFIP1 (Q6WKZ4)
Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein)
Gene: RAB11FIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1210 Hs			1 1283
+	Hs
		338861 EGFR_HUMAN (1-1210): 0: 1241: 100.00		NED4L_HUMAN (20-621): 1.55e-64: 240: 12.03
+	Hs
		338937 EGFR_HUMAN (1-1210): 0: 1241: 100.00		RFIP5_HUMAN (1075-1278): 5.6e-39: 157: 23.87
+	Hs
		338878 EGFR_HUMAN (1-1210): 0: 1241: 100.00		MUC4_HUMAN (136-1246): 9.51e-37: 154: 9.78
+	Hs
		337891 EGFR_HUMAN (1-1210): 0: 1241: 100.00		KPCA_HUMAN (19-174): 1.99e-37: 152: 20.59
+	Hs
		87302 EGFR_HUMAN (1-1210): 0: 1241: 100.00		RAS4B_HUMAN (20-212): 1.17e-21: 103: 14.95
+	Hs
		601981 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		NED4L_HUMAN (20-621): 1.55e-64: 240: 12.03
+	Hs
		339058 EGFR_HUMAN (1-1210): 0: 1241: 100.00		ITSN2_HUMAN (20-129): 3.36e-11: 70.4: 27.27
+	Hs
		338292 EGFR_HUMAN (1-1210): 0: 1241: 100.00		ANK2_HUMAN (161-762): 1.11e-09: 65.4: 16.59
+	Hs
		1071005 ERBB4_HUMAN (1-1199): 0: 1137: 49.46		MUC4_HUMAN (136-1246): 9.51e-37: 154: 9.78
+	Hs
		383946 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		MUC4_HUMAN (136-1246): 9.51e-37: 154: 9.78
+	Hs
		601984 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		MUC4_HUMAN (136-1246): 9.51e-37: 154: 9.78
+	Hs
		201881 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		RASL2_HUMAN (20-212): 1.12e-21: 103: 14.95
+	Hs
		383566 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		NFH_HUMAN (327-645): 7.28e-10: 65.8: 16.52
+	Hs
		48271 EPHA2_HUMAN (665-1016): 5.77e-117: 389: 32.79		ESYT2_HUMAN (20-403): 4.18e-43: 172: 14.71
+	Hs
		665653 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		RFIP5_HUMAN (1075-1278): 5.6e-39: 157: 23.87
+	Hs
		665581 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		ANK2_HUMAN (161-762): 1.11e-09: 65.4: 16.59
+	Hs
		992601 ACK1_HUMAN (691-967): 4.54e-56: 214: 39.58		NED4L_HUMAN (20-621): 1.55e-64: 240: 12.03
+	Hs
		789085 ABL2_HUMAN (707-974): 5.53e-52: 202: 40.37		NED4L_HUMAN (20-621): 1.55e-64: 240: 12.03
+	Mm
		222826 ACK1_MOUSE (691-967): 2.4e-53: 206: 38.87		NEDD4_MOUSE (20-397): 1.73e-48: 189: 14.95
+	Mm
		222869 ACK1_MOUSE (691-967): 2.4e-53: 206: 38.87		ANK2_MOUSE (131-1108): 1.32e-31: 137: 14.48