Protein: NOE2
Noelin-2 (Olfactomedin-2)

Gene: NOE2, OLFM2
Organism: Homo sapiens
Interactions: 106
UniProt ID: O95897

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

350734

NOE1
Noelin

4

10

High-throughput

0.892

High

350732

NOE3
Noelin-3

2

10

High-throughput

0.811

High

154787

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

7

High-throughput

0.691

High

159453

DVL2
Segment polarity protein dishevelled homolog DVL-2

2

3

High-throughput

0.628

High

272591

BRE1B
E3 ubiquitin-protein ligase BRE1B

2

2

High-throughput

0.628

High

337929

CNEP1
CTD nuclear envelope phosphatase 1

2

1

High-throughput

0.628

High

350685

BMP7
Bone morphogenetic protein 7

2

1

High-throughput

0.628

High

350706

PEX6
Peroxisomal ATPase PEX6

2

1

High-throughput

0.628

High

350748

DNJB9
DnaJ homolog subfamily B member 9

2

3

High-throughput

0.628

High

350750

EGFL7
Epidermal growth factor-like protein 7

2

6

High-throughput

0.628

High

350753

FEM1B
Protein fem-1 homolog B

2

1

High-throughput

0.628

High

350743

SDF2L
Stromal cell-derived factor 2-like protein 1

3

2

High-throughput

0.604

High

350690

KDM5C
Lysine-specific demethylase 5C

2

0

High-throughput

0.602

High

350711

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

2

0

High-throughput

0.602

High

350717

ZFHX4
Zinc finger homeobox protein 4

2

0

High-throughput

0.602

High

350721

BANP
Protein BANP

2

0

High-throughput

0.602

High

350724

ZN507
Zinc finger protein 507

2

0

High-throughput

0.602

High

350731

VCIP1
Deubiquitinating protein VCPIP1

2

0

High-throughput

0.602

High

350736

HAUS8
HAUS augmin-like complex subunit 8

2

0

High-throughput

0.602

High

350737

MSTO1
Protein misato homolog 1

2

0

High-throughput

0.602

High

350740

TBB1
Tubulin beta-1 chain

2

0

High-throughput

0.602

High

350754

GPTC8
G patch domain-containing protein 8

2

0

High-throughput

0.602

High

350752

FBX2
F-box only protein 2

2

3

High-throughput

0.601

High

350712

OLM2A
Olfactomedin-like protein 2A

1

10

High-throughput

0.575

High

350710

OFUT4
GDP-fucose protein O-fucosyltransferase 4

2

1

High-throughput

0.574

High

350714

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

2

1

High-throughput

0.574

High

350719

KRA13
Keratin-associated protein 1-3

2

5

High-throughput

0.553

High

350694

F10A1
Hsc70-interacting protein

1

2

High-throughput

0.541

High

262356

DTNB
Dystrobrevin beta

1

1

High-throughput

0.536

High

273739

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

2

High-throughput

0.536

High

278200

NCOR1
Nuclear receptor corepressor 1

1

1

High-throughput

0.536

High

350672

C1QB
Complement C1q subcomponent subunit B

1

4

High-throughput

0.536

High

350673

KLK1
Kallikrein-1

1

3

High-throughput

0.536

High

350674

PAEP
Glycodelin

1

2

High-throughput

0.536

High

350680

PRG2
Bone marrow proteoglycan

1

2

High-throughput

0.536

High

350683

PGFRA
Platelet-derived growth factor receptor alpha

1

1

High-throughput

0.536

High

350684

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

1

High-throughput

0.536

High

350687

IDS
Iduronate 2-sulfatase

1

1

High-throughput

0.536

High

350689

GALNS
N-acetylgalactosamine-6-sulfatase

1

1

High-throughput

0.536

High

350696

MFAP4
Microfibril-associated glycoprotein 4

1

2

High-throughput

0.536

High

350698

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

2

High-throughput

0.536

High

350702

IL5RA
Interleukin-5 receptor subunit alpha

1

3

High-throughput

0.536

High

350725

CA054
Uncharacterized protein C1orf54

1

1

High-throughput

0.536

High

350728

ESPB1
Epididymal sperm-binding protein 1

1

2

High-throughput

0.536

High

350745

FBX6
F-box only protein 6

1

3

High-throughput

0.536

High

350746

CBLN4
Cerebellin-4

1

4

High-throughput

0.536

High

350756

FBX7
F-box only protein 7

1

1

High-throughput

0.536

High

350699

KR103
Keratin-associated protein 10-3

2

5

High-throughput

0.533

High

350704

SRSF5
Serine/arginine-rich splicing factor 5

1

0

High-throughput

0.518

High

350678

NT2NC
Notch homolog 2 N-terminal-like protein C

1

5

High-throughput

0.515

High

316646

LY6H
Lymphocyte antigen 6H

1

0

High-throughput

0.513

High

327020

NXPH3
Neurexophilin-3

1

0

High-throughput

0.513

High

342476

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.513

High

350670

SG1D1
Secretoglobin family 1D member 1

1

0

High-throughput

0.513

High

350671

GLHA
Glycoprotein hormones alpha chain

1

0

High-throughput

0.513

High

350675

GIP
Gastric inhibitory polypeptide

1

0

High-throughput

0.513

High

350676

PPBI
Intestinal-type alkaline phosphatase

1

0

High-throughput

0.513

High

350677

CFC1
Cryptic protein

1

0

High-throughput

0.513

High

350681

EDN3
Endothelin-3

1

0

High-throughput

0.513

High

350686

C4BPB
C4b-binding protein beta chain

1

0

High-throughput

0.513

High

350688

CAH6
Carbonic anhydrase 6

1

0

High-throughput

0.513

High

350692

CXCL5
C-X-C motif chemokine 5

1

0

High-throughput

0.513

High

350693

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.513

High

350695

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.513

High

350716

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

0

High-throughput

0.513

High

350718

TMM25
Transmembrane protein 25

1

0

High-throughput

0.513

High

350720

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.513

High

350722

FIBIN
Fin bud initiation factor homolog

1

0

High-throughput

0.513

High

350726

N42L2
NEDD4-binding protein 2-like 2

1

0

High-throughput

0.513

High

350727

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

350733

CGRE1
Cell growth regulator with EF hand domain protein 1

1

0

High-throughput

0.513

High

350739

CST11
Cystatin-11

1

0

High-throughput

0.513

High

350747

NSE4A
Non-structural maintenance of chromosomes element 4 homolog A

1

0

High-throughput

0.513

High

350757

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.513

High

85934

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

3

High-throughput

0.489

High

350723

SHKB1
SH3KBP1-binding protein 1

1

2

High-throughput

0.489

High

350738

BOC
Brother of CDO

1

1

High-throughput

0.489

High

350751

BTNL2
Butyrophilin-like protein 2

1

2

High-throughput

0.489

High

350715

NT2NA
Notch homolog 2 N-terminal-like protein A

1

4

High-throughput

0.481

High

454

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.460

High

350755

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

1

0

High-throughput

0.460

High

350682

KPYM
Pyruvate kinase PKM

1

1

High-throughput

0.457

High

350679

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.445

High

350697

LAMB2
Laminin subunit beta-2

1

2

High-throughput

0.445

High

350700

LCN6
Epididymal-specific lipocalin-6

1

2

High-throughput

0.445

High

350707

LAMB3
Laminin subunit beta-3

1

3

High-throughput

0.445

High

350708

LAMC2
Laminin subunit gamma-2

1

5

High-throughput

0.445

High

350749

SE1L1
Protein sel-1 homolog 1

1

2

High-throughput

0.445

High

350703

KRA11
Keratin-associated protein 1-1

1

5

High-throughput

0.439

High

163607

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

0

High-throughput

0.438

High

350691

EIF1
Eukaryotic translation initiation factor 1

1

0

High-throughput

0.438

High

350701

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.438

High

350744

FANCF
Fanconi anemia group F protein

1

0

High-throughput

0.438

High

350730

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

0

High-throughput

0.426

High

350709

RB11B
Ras-related protein Rab-11B

1

1

High-throughput

0.417

High

170600

CLGN
Calmegin

1

6

High-throughput

0.407

High

350705

OS9
Protein OS-9

1

2

High-throughput

0.407

High

350729

ERLEC
Endoplasmic reticulum lectin 1

1

2

High-throughput

0.407

High

67452

ZSWM8
Zinc finger SWIM domain-containing protein 8

2

0

High-throughput

0.328

High

155822

DPYL4
Dihydropyrimidinase-related protein 4

2

0

High-throughput

0.328

High

350713

CO039
Uncharacterized protein C15orf39

2

0

High-throughput

0.328

High

168357

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.279

Low

350735

TM2D3
TM2 domain-containing protein 3

1

0

High-throughput

0.279

Low

350741

UD110
UDP-glucuronosyltransferase 1A10

1

0

High-throughput

0.279

Low

60283

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.238

Low

350742

ROBO2
Roundabout homolog 2

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025