HitPredict

Interactor 1: NFAC1 (O95644)
Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc)
Gene: NFATC1

Interactor 2: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27637333
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 943 Hs			1 654
+	Hs
		626096 NFKB1_HUMAN (380-782): 8.43e-99: 334: 16.59		HS71L_HUMAN (24-647): 0: 919: 63.16
+	Mm
		681984 NFKB1_MOUSE (380-832): 3.31e-103: 346: 14.97		HS71A_MOUSE (26-635): 0: 903: 63.46
+	Hs
		536476 NFKB1_HUMAN (380-782): 8.43e-99: 334: 16.59		HSP7C_HUMAN (26-637): 0: 914: 66.02
+	Hs
		761375 REL_HUMAN (419-924): 1.07e-100: 329: 15.34		HS71L_HUMAN (24-647): 0: 919: 63.16
+	Hs
		534617 NFKB1_HUMAN (380-782): 8.43e-99: 334: 16.59		BIP_HUMAN (19-654): 0: 913: 100.00
+	Hs
		600730 NFKB1_HUMAN (380-782): 8.43e-99: 334: 16.59		HSP76_HUMAN (25-635): 0: 913: 62.54
+	Hs
		537019 REL_HUMAN (419-924): 1.07e-100: 329: 15.34		HSP7C_HUMAN (26-637): 0: 914: 66.02
+	Hs
		534963 REL_HUMAN (419-924): 1.07e-100: 329: 15.34		BIP_HUMAN (19-654): 0: 913: 100.00
+	Hs
		600795 REL_HUMAN (419-924): 1.07e-100: 329: 15.34		HSP76_HUMAN (25-635): 0: 913: 62.54
+	Hs
		626132 NFKB1_HUMAN (380-782): 8.43e-99: 334: 16.59		HSP72_HUMAN (25-636): 0: 903: 64.51
+	Hs
		537107 NFAC2_HUMAN (37-937): 2.92e-88: 304: 40.50		HSP7C_HUMAN (26-637): 0: 914: 66.02
+	Hs
		535023 NFAC2_HUMAN (37-937): 2.92e-88: 304: 40.50		BIP_HUMAN (19-654): 0: 913: 100.00
+	Hs
		761371 NFKB2_HUMAN (410-852): 1.74e-78: 276: 17.67		HS71L_HUMAN (24-647): 0: 919: 63.16
+	Hs
		536980 NFKB2_HUMAN (410-852): 1.74e-78: 276: 17.67		HSP7C_HUMAN (26-637): 0: 914: 66.02
+	Hs
		534939 NFKB2_HUMAN (410-852): 1.74e-78: 276: 17.67		BIP_HUMAN (19-654): 0: 913: 100.00
+	Hs
		600792 NFKB2_HUMAN (410-852): 1.74e-78: 276: 17.67		HSP76_HUMAN (25-635): 0: 913: 62.54
+	Hs
		761372 RELB_HUMAN (317-856): 4.2e-77: 265: 14.46		HS71L_HUMAN (24-647): 0: 919: 63.16
+	Hs
		536988 RELB_HUMAN (317-856): 4.2e-77: 265: 14.46		HSP7C_HUMAN (26-637): 0: 914: 66.02
+	Hs
		534944 RELB_HUMAN (317-856): 4.2e-77: 265: 14.46		BIP_HUMAN (19-654): 0: 913: 100.00
+	Hs
		600793 RELB_HUMAN (317-856): 4.2e-77: 265: 14.46		HSP76_HUMAN (25-635): 0: 913: 62.54