HitPredict

Interactor 1: TRY1 (P00760)
Serine protease 1 (EC 3.4.21.4) (Anionic trypsin I) (Anionic trypsin-I) (Beta-trypsin) (Cationic trypsin) (Pretrypsinogen I) (Trypsin I) (Trypsin-I) [Cleaved into: Alpha-trypsin chain 1; Alpha-trypsin chain 2]
Gene: PRSS1

Interactor 2: BPT1 (P00974)
Pancreatic trypsin inhibitor (Aprotinin) (Basic protease inhibitor) (BPI) (BPTI)
Gene: BPT1

Species: Bos taurus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.820

The method score is based on:

Property Details
Experiments 24034223, 10222201
Identification Methods comigration in gel electrophoresis, x-ray crystallography, comigration in sds page, differential scanning calorimetry, molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Kunitz_BPTI~Trypsin
Common GO terms GO:0005615 - extracellular space
GO:0097180 - serine protease inhibitor complex
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 246
Bt

1 100
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024