Protein: TONSL
Tonsoku-like protein (Inhibitor of kappa B-related protein) (I-kappa-B-related protein) (IkappaBR) (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2)

Gene: TONSL
Organism: Homo sapiens
Interactions: 93
UniProt ID: Q96HA7

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0016604 - nuclear body
GO:0031297 - replication fork processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

980137

H4
Histone H4

4

5

High-throughput

0.886

High

799390

BRCA1
Breast cancer type 1 susceptibility protein

2

20

High-throughput

0.754

High

1392816

TONSL
Tonsoku-like protein

2

16

Small-scale

0.754

High

1065359

SSRP1
FACT complex subunit SSRP1

6

6

Small-scale

0.735

High

1392828

ASF1B
Histone chaperone ASF1B

6

1

Small-scale

0.734

High

1392832

ASF1A
Histone chaperone ASF1A

6

1

Small-scale

0.733

High

998678

H31
Histone H3.1

6

10

High-throughput

0.729

High

888253

MCM2
DNA replication licensing factor MCM2

4

10

Small-scale

0.694

High

158486

RFXK
DNA-binding protein RFXANK

1

17

High-throughput

0.691

High

1392833

SGT1
Protein SGT1 homolog

1

11

Small-scale

0.691

High

1381842

H2B1A
Histone H2B type 1-A

4

11

High-throughput

0.691

High

591787

H2AX
Histone H2AX

3

16

High-throughput

0.667

High

1253825

MMS22
Protein MMS22-like

4

0

Small-scale

0.657

High

891736

GSK3B
Glycogen synthase kinase-3 beta

1

18

High-throughput

0.656

High

1128261

MCM6
DNA replication licensing factor MCM6

3

10

Small-scale

0.656

High

1392829

H2AW
Core histone macro-H2A.2

2

17

High-throughput

0.628

High

1151495

IKBB
NF-kappa-B inhibitor beta

1

19

High-throughput

0.618

High

1392836

NPTN
Neuroplastin

1

15

High-throughput

0.618

High

414407

P53
Cellular tumor antigen p53

1

8

High-throughput

0.618

High

831239

CCNF
Cyclin-F

1

9

High-throughput

0.618

High

1115904

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

14

High-throughput

0.618

High

1255059

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

755770

MCM4
DNA replication licensing factor MCM4

2

9

Small-scale

0.611

High

1392834

SP16H
FACT complex subunit SPT16

2

1

Small-scale

0.611

High

419136

H2A1B
Histone H2A type 1-B/E

3

13

Small-scale

0.609

High

1392830

DAXX
Death domain-associated protein 6

2

0

High-throughput

0.602

High

412431

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.553

High

182724

GP182
G-protein coupled receptor 182

2

7

High-throughput

0.549

High

1101628

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

6

High-throughput

0.549

High

372841

MYC
Myc proto-oncogene protein

1

11

High-throughput

0.541

High

564208

CFTR
Cystic fibrosis transmembrane conductance regulator

1

6

High-throughput

0.541

High

1033150

EWS
RNA-binding protein EWS

1

11

High-throughput

0.541

High

348658

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

4

Small-scale

0.536

High

418357

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.536

High

558329

XRCC6
X-ray repair cross-complementing protein 6

1

6

Small-scale

0.536

High

559455

XRCC5
X-ray repair cross-complementing protein 5

1

6

Small-scale

0.536

High

595557

H15
Histone H1.5

1

6

Small-scale

0.536

High

1017115

H33
Histone H3.3

1

10

High-throughput

0.536

High

1041789

PPARD
Peroxisome proliferator-activated receptor delta

1

17

High-throughput

0.536

High

1323954

H2B3B
Histone H2B type 3-B

1

11

High-throughput

0.536

High

1329809

SIR6
NAD-dependent protein deacylase sirtuin-6

1

7

High-throughput

0.536

High

1383807

EFMT3
EEF1A lysine methyltransferase 3

1

5

High-throughput

0.536

High

1392820

H2B1L
Histone H2B type 1-L

1

11

Small-scale

0.536

High

1392822

UBXN6
UBX domain-containing protein 6

1

2

High-throughput

0.536

High

1392824

SENP3
Sentrin-specific protease 3

1

2

High-throughput

0.536

High

1392826

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.536

High

1392831

HSPB8
Heat shock protein beta-8

1

5

High-throughput

0.536

High

1219529

ANR22
Ankyrin repeat domain-containing protein 22

1

18

High-throughput

0.514

High

1239271

ARMC6
Armadillo repeat-containing protein 6

1

1

High-throughput

0.514

High

417677

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.489

High

424994

ADT2
ADP/ATP translocase 2

1

3

Small-scale

0.489

High

502480

H2A1
Histone H2A type 1

1

13

High-throughput

0.489

High

505192

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

3

High-throughput

0.489

High

596298

H12
Histone H1.2

1

6

Small-scale

0.489

High

1024431

S25A3
Solute carrier family 25 member 3

1

6

Small-scale

0.489

High

1162867

H2A2C
Histone H2A type 2-C

1

13

High-throughput

0.489

High

1232710

H2A2A
Histone H2A type 2-A

1

13

High-throughput

0.489

High

1349814

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

1

High-throughput

0.489

High

1392817

IMP1L
Mitochondrial inner membrane protease subunit 1

1

5

High-throughput

0.489

High

1392819

NPAS1
Neuronal PAS domain-containing protein 1

1

5

High-throughput

0.489

High

1392821

H2AJ
Histone H2A.J

1

13

High-throughput

0.489

High

1392823

DNAI2
Dynein axonemal intermediate chain 2

1

13

High-throughput

0.489

High

1392835

GPR45
Probable G-protein coupled receptor 45

1

3

High-throughput

0.489

High

242578

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.479

High

277778

H2AY
Core histone macro-H2A.1

1

17

High-throughput

0.479

High

279456

TULP3
Tubby-related protein 3

1

4

High-throughput

0.479

High

447314

NPM
Nucleophosmin

1

7

High-throughput

0.479

High

520285

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

669971

MCM3
DNA replication licensing factor MCM3

1

10

Small-scale

0.479

High

674290

BRD2
Bromodomain-containing protein 2

1

17

High-throughput

0.479

High

756012

MCM5
DNA replication licensing factor MCM5

1

9

Small-scale

0.479

High

756303

MCM7
DNA replication licensing factor MCM7

1

9

Small-scale

0.479

High

855493

ATRX
Transcriptional regulator ATRX

1

9

High-throughput

0.479

High

981010

H2B1C
Histone H2B type 1-C/E/F/G/I

1

11

High-throughput

0.479

High

1141260

BRD3
Bromodomain-containing protein 3

1

13

High-throughput

0.479

High

1161999

H31T
Histone H3.1t

1

10

Small-scale

0.479

High

1258914

H32
Histone H3.2

1

10

High-throughput

0.479

High

1338896

NUP43
Nucleoporin Nup43

1

18

High-throughput

0.479

High

1387489

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

20

High-throughput

0.479

High

1392818

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1392825

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1392827

EGLN3
Prolyl hydroxylase EGLN3

1

8

High-throughput

0.479

High

1289798

SHLD2
Shieldin complex subunit 2

1

0

High-throughput

0.458

High

278935

PEX14
Peroxisomal membrane protein PEX14

1

2

High-throughput

0.457

High

1337906

ZNT7
Zinc transporter 7

1

6

High-throughput

0.445

High

1366171

LPAR1
Lysophosphatidic acid receptor 1

1

2

High-throughput

0.445

High

353501

AGR2
Anterior gradient protein 2 homolog

1

4

High-throughput

0.437

High

1276637

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

14

High-throughput

0.437

High

1234023

S35E4
Solute carrier family 35 member E4

1

1

High-throughput

0.407

High

1356181

NPRL2
GATOR1 complex protein NPRL2

1

0

High-throughput

0.279

Low

1224807

AP1AR
AP-1 complex-associated regulatory protein

1

0

High-throughput

0.249

Low

1226496

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025