HitPredict

Interactor 1: ANR28 (O15084)
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK)
Gene: ANKRD28

Interactor 2: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 23414517, 24255178
Identification Methods two hybrid, proximity labelling technology, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank, Ank~Ank_2, Ank_2~Ank_2
Common GO terms GO:0005654 - nucleoplasm
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1053
Hs

1 2471
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Service provided by Combinatics, Japan

Last updated: 11Aug2025