HitPredict

Interactor 1: HERC2 (O95714)
E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2)
Gene: HERC2

Interactor 2: BICD1 (Q96G01)
Protein bicaudal D homolog 1 (Bic-D 1)
Gene: BICD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25476789, 28718761
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 4834 Hs			1 975
+	Hs
		342976 HERC2_HUMAN (1-4834): 0: 6292: 100.00		BICD2_HUMAN (6-812): 7.25e-59: 219: 62.93
+	Mm
		1196077 HERC2_MOUSE (1-4834): 0: 6295: 95.51		MYH10_MOUSE (558-962): 9.1e-16: 84.8: 10.60
+	Hs
		342900 HERC2_HUMAN (1-4834): 0: 6292: 100.00		GRDN_HUMAN (3-772): 1.61e-11: 70.7: 19.78
+	Hs
		1191481 WWP1_HUMAN (4321-4794): 1.79e-168: 549: 21.37		GRDN_HUMAN (3-772): 1.61e-11: 70.7: 19.78
+	Hs
		1191488 SMUF1_HUMAN (4280-4794): 2.43e-160: 519: 19.71		GRDN_HUMAN (3-772): 1.61e-11: 70.7: 19.78
+	Hs
		587813 SMUF1_HUMAN (4280-4794): 2.43e-160: 519: 19.71		DESP_HUMAN (4-472): 2.08e-10: 67.2: 18.80
+	Hs
		772879 HUWE1_HUMAN (4365-4788): 3.25e-118: 426: 24.00		MYH9_HUMAN (558-936): 1.96e-15: 83.6: 10.39
+	Hs
		1191435 HUWE1_HUMAN (4365-4788): 3.25e-118: 426: 24.00		GRDN_HUMAN (3-772): 1.61e-11: 70.7: 19.78
+	Hs
		587717 NEK8_HUMAN (4165-4333): 2.82e-09: 65.9: 29.23		DESP_HUMAN (4-472): 2.08e-10: 67.2: 18.80