Protein: AK1C2
Aldo-keto reductase family 1 member C2 (EC 1.-.-.-) (EC 1.1.1.112) (EC 1.1.1.209) (EC 1.1.1.53) (EC 1.1.1.62) (EC 1.3.1.20) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) (Dihydrodiol dehydrogenase 2) (DD-2) (DD2) (Dihydrodiol dehydrogenase/bile acid-binding protein) (DD/BABP) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.357)

Gene: AK1C2, AKR1C2
Organism: Homo sapiens
Interactions: 30
UniProt ID: P52895

Gene Ontology (top 5):
GO:0004032 - aldose reductase (NADPH) activity
GO:0004303 - estradiol 17-beta-dehydrogenase [NAD(P)+] activity
GO:0005829 - cytosol
GO:0006693 - prostaglandin metabolic process
GO:0007186 - G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

568053

AK1C4
Aldo-keto reductase family 1 member C4

3

11

High-throughput

0.861

High

787129

AK1C3
Aldo-keto reductase family 1 member C3

3

11

High-throughput

0.861

High

857069

AK1C1
Aldo-keto reductase family 1 member C1

3

11

High-throughput

0.861

High

178134

IPO8
Importin-8

2

1

High-throughput

0.611

High

857071

ZFP1
Zinc finger protein 1 homolog

3

1

High-throughput

0.609

High

857065

AK1C2
Aldo-keto reductase family 1 member C2

1

10

Small-scale

0.575

High

176415

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

3

High-throughput

0.536

High

565902

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.536

High

857074

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.536

High

206340

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.518

High

686622

CCR1
C-C chemokine receptor type 1

1

3

High-throughput

0.489

High

857075

SRRT
Serrate RNA effector molecule homolog

1

2

High-throughput

0.489

High

857077

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

1

2

High-throughput

0.489

High

128828

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

2

High-throughput

0.479

High

373921

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

397860

ISG15
Ubiquitin-like protein ISG15

1

3

High-throughput

0.479

High

857066

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.479

High

857068

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.479

High

857072

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.479

High

857076

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

329527

AGR2
Anterior gradient protein 2 homolog

1

3

High-throughput

0.470

High

455250

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

742149

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

244158

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.437

High

857067

VIGLN
Vigilin

1

1

High-throughput

0.437

High

857070

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

4

High-throughput

0.437

High

857073

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.279

Low

547484

FOLR1
Folate receptor alpha

1

0

High-throughput

0.249

Low

815200

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024