HitPredict

Interactor 1: RAB3D (O95716)
Ras-related protein Rab-3D (EC 3.6.5.2)
Gene: RAB3D

Interactor 2: MSS4 (P47224)
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)
Gene: RABIF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Mss4~Ras
Common GO terms	GO:0015031 - protein transport
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 219 Hs			1 123
+	Hs
		866388 RAB8B_HUMAN (17-212): 1.25e-99: 289: 47.96		MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00
+	Hs
		866373 RAB1A_HUMAN (12-219): 1.11e-91: 269: 43.75		MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00
+	Mm
		981414 RAB1A_MOUSE (12-219): 1.11e-91: 269: 43.75		MSS4_MOUSE (1-123): 1.16e-71: 211: 93.50
+	Hs
		866394 RAB1B_HUMAN (15-219): 4.7e-89: 262: 43.90		MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00
+	Hs
		630469 RAB3B_HUMAN (1-219): 2.68e-86: 255: 75.80		MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00
+	Hs
		866389 RAB3C_HUMAN (1-219): 4.47e-85: 253: 73.52		MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00
+	Hs
		630405 RAB3A_HUMAN (1-219): 3.08e-84: 250: 76.82		MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00
+	Hs
		866371 RAB8A_HUMAN (15-214): 2.96e-84: 250: 50.00		MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00
+	Dm
		670095 RAB3_DROME (1-219): 1.6e-88: 261: 74.66		MSS4_DROME (13-123): 3.16e-52: 162: 39.29
+	Dm
		197103 O18332_DROME (12-219): 1.07e-86: 256: 43.27		MSS4_DROME (13-123): 3.16e-52: 162: 39.29
+	Hs
		866372 RAB10_HUMAN (15-201): 2.58e-66: 204: 50.26		MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00
+	Dm
		194907 O15971_DROME (15-186): 2.86e-64: 199: 52.91		MSS4_DROME (13-123): 3.16e-52: 162: 39.29
+	Dm
		197420 O18338_DROME (17-195): 1.85e-62: 195: 50.28		MSS4_DROME (13-123): 3.16e-52: 162: 39.29