HitPredict

Interactor 1: MSS4 (P47224)
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)
Gene: RABIF

Interactor 2: RAB3C (Q96E17)
Ras-related protein Rab-3C (EC 3.6.5.2)
Gene: RAB3C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Mss4~Ras
Common GO terms	GO:0015031 - protein transport
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 123 Hs			1 227
+	Hs
		866373 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB1A_HUMAN (20-227): 1.23e-90: 266: 43.27
+	Mm
		981414 MSS4_MOUSE (1-123): 1.16e-71: 211: 93.50		RAB1A_MOUSE (20-227): 1.23e-90: 266: 43.27
+	Hs
		630405 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB3A_HUMAN (9-227): 1.16e-89: 265: 83.64
+	Hs
		866394 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB1B_HUMAN (23-227): 1.58e-87: 258: 42.44
+	Hs
		343172 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB3D_HUMAN (9-227): 1.21e-83: 249: 73.52
+	Hs
		630469 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB3B_HUMAN (9-227): 1.25e-83: 249: 80.82
+	Hs
		866371 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB8A_HUMAN (23-222): 1.16e-83: 249: 48.50
+	Dm
		670095 MSS4_DROME (13-123): 3.16e-52: 162: 39.29		RAB3_DROME (9-227): 3.84e-90: 266: 78.73
+	Dm
		197103 MSS4_DROME (13-123): 3.16e-52: 162: 39.29		O18332_DROME (20-226): 7.16e-87: 257: 42.03
+	Hs
		866388 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB8B_HUMAN (25-199): 3.75e-64: 199: 52.00
+	Hs
		866372 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB10_HUMAN (23-194): 2.33e-63: 197: 52.33
+	Dm
		194907 MSS4_DROME (13-123): 3.16e-52: 162: 39.29		O15971_DROME (23-226): 2.51e-67: 207: 50.00
+	Dm
		197420 MSS4_DROME (13-123): 3.16e-52: 162: 39.29		O18338_DROME (25-202): 1.08e-62: 196: 51.12