Interactor 1: TRPG (P00937)
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2 (AS) (EC 4.1.3.27) (Anthranilate synthase, glutamine amidotransferase component); Indole-3-glycerol phosphate synthase (EC 4.1.1.48) (PRAI)]
Gene: TRP3

Interactor 2: PYR1 (P07259)
Multifunctional protein URA2 (Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase) (CPSase-ATCase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5) (Carbamoyl phosphate synthase P) (CPS-P) (CPSase P) (CPSase-ura) (Pyrimidine-specific carbamoyl phosphate synthase); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (ATCase) (EC 2.1.3.2) (Aspartate transcarbamylase)]
Gene: URA2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 16429126
Identification Methods tandem affinity purification
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains CPSase_L_D2~GATase, CPSase_sm_chain~GATase, GATase~GATase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006541 - glutamine metabolic process
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 484
Sc

1 2214
+ Hs
+ Sc
+ Sc
+ At
+ Ec
+ Nv
+ Ec
+ Hs
+ Pf

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Last updated: 15 Jul 2024