Protein: CLOCK
Circadian locomoter output cycles protein kaput (mCLOCK) (EC 2.3.1.48)

Gene: CLOCK
Organism: Mus musculus
Interactions: 27
UniProt ID: O08785

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

139879

BMAL1
Basic helix-loop-helix ARNT-like protein 1

22

20

Small-scale

0.989

High

139857

PER2
Period circadian protein homolog 2

8

19

Small-scale

0.960

High

139856

PER1
Period circadian protein homolog 1

3

19

Small-scale

0.827

High

139864

CRY1
Cryptochrome-1

9

16

Small-scale

0.749

High

139873

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

10

Small-scale

0.649

High

139878

CRY2
Cryptochrome-2

3

16

Small-scale

0.636

High

139858

PER3
Period circadian protein homolog 3

1

20

Small-scale

0.618

High

139865

BMAL2
Basic helix-loop-helix ARNT-like protein 2

1

20

Small-scale

0.590

High

139875

BHE41
Class E basic helix-loop-helix protein 41

1

5

High-throughput

0.590

High

101411

F8VPR5
histone acetyltransferase

2

20

Small-scale

0.584

High

139860

KPCA
Protein kinase C alpha type

1

6

Small-scale

0.561

High

139861

KMT2A
Histone-lysine N-methyltransferase 2A

1

8

Small-scale

0.536

High

139877

KC1E
Casein kinase I isoform epsilon

1

10

High-throughput

0.506

High

139862

H4
Histone H4

1

6

Small-scale

0.501

High

139863

KPCG
Protein kinase C gamma type

1

6

Small-scale

0.501

High

64269

WDR76
WD repeat-containing protein 76

1

8

Small-scale

0.500

High

139866

DDB1
DNA damage-binding protein 1

1

7

Small-scale

0.500

High

139867

EZH2
Histone-lysine N-methyltransferase EZH2

1

10

Small-scale

0.479

High

139868

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

3

High-throughput

0.479

High

139870

RAE1L
mRNA export factor

1

5

Small-scale

0.479

High

139871

KAT5
Histone acetyltransferase KAT5

1

3

Small-scale

0.479

High

139876

KAT2B
Histone acetyltransferase KAT2B

1

20

Small-scale

0.479

High

139869

NUP98
Nuclear pore complex protein Nup98-Nup96

1

0

Small-scale

0.458

High

139872

CIPC
CLOCK-interacting pacemaker

1

4

High-throughput

0.457

High

139874

Q99JJ1
Cry2 protein

1

16

Small-scale

0.457

High

56919

PRD16
Histone-lysine N-methyltransferase PRDM16

1

1

Small-scale

0.445

High

139859

PARP1
Poly [ADP-ribose] polymerase 1

1

7

Small-scale

0.445

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024