Interactor 1: CO3 (P01024)
Complement C3 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1) [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2]
Gene: C3
Interactor 2: VSIG4 (Q9Y279)
V-set and immunoglobulin domain-containing protein 4 (Protein Z39Ig)
Gene: VSIG4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.690 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16530040 |
| Identification Methods | surface plasmon resonance, enzyme linked immunosorbent assay, fluorescence-activated cell sorting |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | A2M~V-set, A2M_BRD~V-set, ANATO~V-set, MG1~V-set, MG3~V-set, MG4~V-set |
| Common GO terms | GO:0006957 - complement activation, alternative pathway GO:0032991 - protein-containing complex |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
