HitPredict

Interactor 1: CYTA (P01040)
Cystatin-A (Cystatin-AS) (Stefin-A) [Cleaved into: Cystatin-A, N-terminally processed]
Gene: CSTA

Interactor 2: CATL1 (P07711)
Procathepsin L (EC 3.4.22.15) (Cathepsin L1) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L; Cathepsin L heavy chain; Cathepsin L light chain]
Gene: CTSL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.857

Property	Details
Experiments	12921779, 9585570, 33961781
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Cystatin~Peptidase_C1
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 98 Hs			1 333
+	Hs
		376059 CYTB_HUMAN (1-98): 7.38e-54: 164: 53.06		CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00
+	Hs
		245771 CYTA_HUMAN (1-98): 2.93e-49: 152: 100.00		CATL2_HUMAN (1-333): 1.72e-170: 478: 77.25
+	Hs
		376061 CYTB_HUMAN (1-98): 7.38e-54: 164: 53.06		CATH_HUMAN (2-332): 6.44e-128: 370: 37.28
+	Hs
		345047 CYTA_HUMAN (1-98): 2.93e-49: 152: 100.00		CATH_HUMAN (2-332): 6.44e-128: 370: 37.28
+	Hs
		376119 CYTB_HUMAN (1-98): 7.38e-54: 164: 53.06		CATF_HUMAN (25-333): 1.1e-104: 316: 36.74
+	Hs
		345149 CYTA_HUMAN (1-98): 2.93e-49: 152: 100.00		CATF_HUMAN (25-333): 1.1e-104: 316: 36.74