HitPredict

Interactor 1: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0034614 - cellular response to reactive oxygen species
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 284
+	Hs
		345283 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20
+	Hs
		345393 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72
+	Hs
		451186 ATF2_HUMAN (4-283): 3.58e-29: 119: 18.57		TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00
+	Hs
		418865 ATF2_HUMAN (4-283): 3.58e-29: 119: 18.57		TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20
+	Hs
		418870 JUNB_HUMAN (85-215): 3.19e-25: 106: 19.86		TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20
+	Hs
		401292 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00
+	Hs
		401268 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20
+	Hs
		547777 ATF2_HUMAN (4-283): 3.58e-29: 119: 18.57		TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72
+	Hs
		451187 JUND_HUMAN (112-215): 1.79e-13: 72.8: 20.00		TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00
+	Hs
		579190 ATF3_HUMAN (131-215): 4.23e-25: 102: 43.53		TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72
+	Hs
		418871 JUND_HUMAN (112-215): 1.79e-13: 72.8: 20.00		TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20
+	Hs
		3155 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		A0A0S2Z4G4_HUMAN (1-242): 2.69e-14: 72.7: 23.97