HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: ANXA2 (P07355)
Annexin A2 (Annexin II) (Annexin-2) (Calpactin I heavy chain) (Calpactin-1 heavy chain) (Chromobindin-8) (Lipocortin II) (Placental anticoagulant protein IV) (PAP-IV) (Protein I) (p36)
Gene: ANXA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	30081903, 35013218, 36424410, 21150319
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 339
+	Hs
		345742 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ANXA5_HUMAN (24-339): 5.27e-160: 451: 46.20
+	Hs
		345652 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ANXA1_HUMAN (1-338): 4.33e-159: 450: 50.72
+	Hs
		427437 TFEB_HUMAN (180-450): 2.56e-28: 118: 14.59		ANXA2_HUMAN (1-339): 3.16e-174: 488: 100.00
+	Hs
		345905 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ANXA7_HUMAN (191-338): 7.11e-30: 120: 28.19