HitPredict

Interactor 1: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: CYH4 (Q9UIA0)
Cytohesin-4 (PH, SEC7 and coiled-coil domain-containing protein 4)
Gene: CYTH4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 394
+	Hs
		1074114 BACH2_HUMAN (14-307): 4.1e-34: 136: 13.65		CYH1_HUMAN (8-394): 5.46e-169: 480: 69.85
+	Hs
		157205 BACH1_HUMAN (4-295): 1.68e-30: 125: 12.99		CYH1_HUMAN (8-394): 5.46e-169: 480: 69.85
+	Hs
		548303 FOSL2_HUMAN (2-380): 3.19e-31: 122: 39.54		CYH1_HUMAN (8-394): 5.46e-169: 480: 69.85
+	Hs
		548328 FOSL2_HUMAN (2-380): 3.19e-31: 122: 39.54		CYH2_HUMAN (1-394): 2.27e-168: 478: 68.10
+	Hs
		862638 FOSB_HUMAN (2-380): 1.59e-25: 107: 34.24		CYH4_HUMAN (1-394): 2.1e-171: 485: 100.00
+	Hs
		212304 FOSL2_HUMAN (2-380): 3.19e-31: 122: 39.54		CYH3_HUMAN (22-394): 2.18e-163: 465: 73.26
+	Hs
		402056 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		CYH1_HUMAN (8-394): 5.46e-169: 480: 69.85
+	Hs
		568095 JUND_HUMAN (112-215): 1.79e-13: 72.8: 20.00		CYH1_HUMAN (8-394): 5.46e-169: 480: 69.85
+	Hs
		1150999 Q6FG41_HUMAN (1-380): 1.68e-84: 263: 100.00		Q8WWE8_HUMAN (1-118): 1.59e-79: 241: 100.00