HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.741

The method score is based on:

Property Details
Experiments 35013218, 36424410, 16574648, 16007074, 17502350, 19652203, 18593917, 25659031
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0001221 - transcription coregulator binding
GO:0001658 - branching involved in ureteric bud morphogenesis
GO:0002053 - positive regulation of mesenchymal cell proliferation
and 11 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 454
Hs

1 781
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024