HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: UBP5 (P45974)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: USP5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	29467282, 36602428
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 858
+	Hs
		347510 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP13_HUMAN (2-858): 0: 721: 59.47
+	Hs
		379106 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		UBP5_HUMAN (1-858): 0: 842: 100.00
+	Hs
		607792 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		UBP5_HUMAN (1-858): 0: 842: 100.00
+	Hs
		252929 MITF_HUMAN (155-450): 1.47e-29: 123: 14.47		UBP13_HUMAN (2-858): 0: 721: 59.47
+	Hs
		348252 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP22_HUMAN (139-682): 5.21e-111: 352: 14.11
+	Hs
		347922 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP42_HUMAN (264-807): 5.1e-86: 301: 11.96
+	Hs
		347511 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		USP9X_HUMAN (289-758): 2.24e-84: 298: 16.20
+	Hs
		348110 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP36_HUMAN (250-817): 9.73e-85: 295: 13.61
+	Hs
		347512 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17
+	Hs
		346960 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP39_HUMAN (133-660): 1.38e-83: 280: 14.87
+	Hs
		64198 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP27_HUMAN (262-682): 6.68e-84: 277: 14.69
+	Hs
		379972 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		UBP36_HUMAN (250-817): 9.73e-85: 295: 13.61
+	Hs
		379685 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17
+	Hs
		379471 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		UBP39_HUMAN (133-660): 1.38e-83: 280: 14.87
+	Hs
		347416 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP33_HUMAN (174-457): 8.74e-23: 106: 21.60
+	Hs
		348388 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP3_HUMAN (702-853): 3.54e-15: 81.2: 16.35
+	Hs
		271012 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP2_HUMAN (700-854): 1.43e-11: 70.1: 16.05
+	Hs
		738985 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17
+	Dm
		1373210 MYC_DROME (210-454): 3.25e-30: 126: 26.74		UBP36_DROME (326-730): 1.08e-20: 100: 16.04