HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: SRSF2 (Q01130)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 221
+	Hs
		346857 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24
+	Hs
		345797 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27
+	Hs
		346655 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79
+	Hs
		346697 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37
+	Hs
		348168 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PUF60_HUMAN (8-108): 1.34e-23: 100: 23.76
+	Hs
		346042 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TIA1_HUMAN (9-184): 2.34e-16: 78.5: 10.67
+	Hs
		346545 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TIAR_HUMAN (9-167): 1.19e-15: 76.6: 9.26
+	Hs
		379435 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24
+	Hs
		378957 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27
+	Hs
		379303 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00
+	Hs
		379345 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79
+	Hs
		379365 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37
+	Hs
		379994 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PUF60_HUMAN (8-108): 1.34e-23: 100: 23.76
+	Hs
		379055 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TIA1_HUMAN (9-184): 2.34e-16: 78.5: 10.67
+	Hs
		379302 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TIAR_HUMAN (9-167): 1.19e-15: 76.6: 9.26
+	Hs
		379406 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ELAV3_HUMAN (115-195): 1.55e-11: 64.6: 11.11