HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DSG1 (Q02413)
Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen)
Gene: DSG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1049
+	Hs
		379306 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DSG1_HUMAN (1-1049): 0: 1147: 100.00
+	Hs
		346753 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DSG2_HUMAN (2-1048): 0: 742: 32.40
+	Hs
		346625 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DSC1_HUMAN (29-765): 0: 574: 24.87
+	Hs
		346339 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CAD13_HUMAN (42-590): 4.77e-155: 478: 27.06
+	Hs
		379329 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DSC1_HUMAN (29-765): 0: 574: 24.87
+	Hs
		345887 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CADH2_HUMAN (19-489): 1.77e-64: 237: 18.71
+	Hs
		346784 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DSC3_HUMAN (1-355): 3.07e-35: 147: 20.27
+	Hs
		60712 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		A5D8W4_HUMAN (306-544): 1.99e-22: 105: 17.00
+	Mm
		454965 TFEB_MOUSE (167-450): 3.76e-30: 123: 14.92		CADH1_MOUSE (19-417): 2.79e-51: 197: 19.90