HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	29467282, 17314511
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 325
+	Hs
		196936 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67
+	Hs
		346404 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		347550 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		346159 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61
+	Hs
		347517 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		348323 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15
+	Mm
		348444 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		FBXW7_MOUSE (5-75): 2.93e-09: 60: 24.05
+	Hs
		379200 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		379701 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		607803 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		297832 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		BRWD3_HUMAN (65-317): 2.08e-26: 112: 15.72
+	Hs
		379688 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		380059 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15
+	Hs
		903353 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Mm
		659344 MAX_MOUSE (354-454): 3.52e-25: 102: 32.67		WDR5_MOUSE (180-325): 1.26e-38: 141: 15.65
+	Hs
		1218698 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Mm
		1112323 SRBP2_MOUSE (124-446): 2.23e-37: 147: 13.60		FBXW7_MOUSE (5-75): 2.93e-09: 60: 24.05
+	Dm
		1375911 MYC_DROME (210-454): 3.25e-30: 126: 26.74		FBXW7_DROME (215-324): 1.96e-15: 79.3: 13.39
+	Mm
		1257396 SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61		FBXW7_MOUSE (5-75): 2.93e-09: 60: 24.05
+	Hs
		738987 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05