Interactor 1: AIFM1 (O95831)
Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8)
Gene: AIFM1
Interactor 2: THIO (P10599)
Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx)
Gene: TXN
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.83 | 1.00 | 0.916 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26119781, 29568061, 33961781, 39422127, unassigned1655 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, cross-linking study, pull down, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pyr_redox_2~Thioredoxin |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025