Interactor 1: TRXR1 (P91938)
Thioredoxin reductase 1, mitochondrial (EC 1.8.1.9)
Gene: TRXR1

Interactor 2: THIO2 (Q9V429)
Thioredoxin-2 (DmTrx-2)
Gene: Trx2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pyr_redox_2~Thioredoxin, Pyr_redox_dim~Thioredoxin
Common GO terms GO:0005829 - cytosol
GO:0008340 - determination of adult lifespan
GO:0045454 - cell redox homeostasis
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 596
Dm

1 106
+ Dm
+ Dm
+ Dm
+ Hs
+ Dm
+ Dm
+ At
+ Ec
+ Ec

Service provided by Combinatics, Japan

Last updated: 11Aug2025