Interactor 1: MYC (P01108)
Myc proto-oncogene protein (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MYCN (P03966)
N-myc proto-oncogene protein
Gene: MYCN

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23665319
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH, HLH~Myc-LZ
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0002053 - positive regulation of mesenchymal cell proliferation
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 454
Mm

1 462
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Gg
+ At
+ Mm
+ At
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024