HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30442766, 30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0044877 - protein-containing complex binding GO:0045445 - myoblast differentiation GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 798
+	Hs
		403931 RAB8B_HUMAN (4-181): 2.25e-85: 251: 36.11		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		349799 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403888 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		349063 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403849 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		349863 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ITB5_HUMAN (19-792): 0: 660: 42.64
+	Hs
		349865 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ITB6_HUMAN (27-798): 0: 643: 41.81
+	Hs
		574519 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		ITB5_HUMAN (19-792): 0: 660: 42.64
+	Hs
		348502 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		ITB6_HUMAN (27-798): 0: 643: 41.81
+	Hs
		349061 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ITB3_HUMAN (25-797): 0: 646: 44.02
+	Hs
		349112 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ITB6_HUMAN (27-798): 0: 643: 41.81
+	Hs
		350636 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		350099 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26
+	Hs
		349957 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		NOTC1_HUMAN (514-747): 1.07e-10: 67.8: 16.80
+	Hs
		980377 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26
+	Hs
		804251 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		NOTC1_HUMAN (514-747): 1.07e-10: 67.8: 16.80
+	Hs
		348629 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26
+	Hs
		348564 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		NOTC1_HUMAN (514-747): 1.07e-10: 67.8: 16.80
+	Hs
		349180 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		NOTC1_HUMAN (514-747): 1.07e-10: 67.8: 16.80
+	Hs
		804192 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		NOTC1_HUMAN (514-747): 1.07e-10: 67.8: 16.80