Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
M3K5
Mitogen-activated protein kinase kinase kinase 5 |
18 |
17 |
Small-scale |
0.986 | High |
|
|
MP2K6
Dual specificity mitogen-activated protein kinase kinase 6 |
9 |
19 |
Small-scale |
0.969 | High |
|
|
MP2K3
Dual specificity mitogen-activated protein kinase kinase 3 |
7 |
17 |
Small-scale |
0.960 | High |
|
|
M3K6
Mitogen-activated protein kinase kinase kinase 6 |
5 |
18 |
Small-scale |
0.924 | High |
|
|
MP2K4
Dual specificity mitogen-activated protein kinase kinase 4 |
5 |
19 |
Small-scale |
0.920 | High |
|
|
CIB1
Calcium and integrin-binding protein 1 |
2 |
20 |
Small-scale |
0.855 | High |
|
|
LATS2
Serine/threonine-protein kinase LATS2 |
2 |
19 |
Small-scale |
0.831 | High |
|
|
RAF1
RAF proto-oncogene serine/threonine-protein kinase |
2 |
20 |
Small-scale |
0.825 | High |
|
|
M3K7
Mitogen-activated protein kinase kinase kinase 7 |
2 |
19 |
Small-scale |
0.815 | High |
|
|
CDN1A
Cyclin-dependent kinase inhibitor 1 |
2 |
9 |
Small-scale |
0.806 | High |
|
|
AKT1
RAC-alpha serine/threonine-protein kinase |
1 |
16 |
Small-scale |
0.780 | High |
|
|
JAK2
Tyrosine-protein kinase JAK2 |
1 |
20 |
Small-scale |
0.770 | High |
|
|
THIO
Thioredoxin |
20 |
6 |
Small-scale |
0.766 | High |
|
|
TRAF2
TNF receptor-associated factor 2 |
13 |
20 |
Small-scale |
0.761 | High |
|
|
MP2K7
Dual specificity mitogen-activated protein kinase kinase 7 |
2 |
17 |
Small-scale |
0.754 | High |
|
|
ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1 |
2 |
18 |
Small-scale |
0.754 | High |
|
|
DAXX
Death domain-associated protein 6 |
7 |
3 |
Small-scale |
0.744 | High |
|
|
TRAF6
TNF receptor-associated factor 6 |
7 |
20 |
Small-scale |
0.741 | High |
|
|
MPIP1
M-phase inducer phosphatase 1 |
1 |
2 |
Small-scale |
0.740 | High |
|
|
1433Z
14-3-3 protein zeta/delta |
6 |
20 |
Small-scale |
0.730 | High |
|
|
PDCD6
Programmed cell death protein 6 |
1 |
9 |
Small-scale |
0.724 | High |
|
|
MPIP3
M-phase inducer phosphatase 3 |
1 |
2 |
Small-scale |
0.724 | High |
|
|
BIRC2
Baculoviral IAP repeat-containing protein 2 |
1 |
17 |
Small-scale |
0.724 | High |
|
|
1433G
14-3-3 protein gamma |
5 |
20 |
Small-scale |
0.716 | High |
|
|
DAB2P
Disabled homolog 2-interacting protein |
5 |
12 |
Small-scale |
0.708 | High |
|
|
SOCS1
Suppressor of cytokine signaling 1 |
4 |
20 |
Small-scale |
0.698 | High |
|
|
AAKB2
5'-AMP-activated protein kinase subunit beta-2 |
1 |
14 |
High-throughput |
0.691 | High |
|
|
MK04
Mitogen-activated protein kinase 4 |
1 |
20 |
High-throughput |
0.691 | High |
|
|
AKT2
RAC-beta serine/threonine-protein kinase |
1 |
16 |
Small-scale |
0.691 | High |
|
|
AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2 |
1 |
19 |
High-throughput |
0.691 | High |
|
|
1433E
14-3-3 protein epsilon |
4 |
20 |
Small-scale |
0.681 | High |
|
|
1433F
14-3-3 protein eta |
4 |
20 |
Small-scale |
0.676 | High |
|
|
ARRB1
Beta-arrestin-1 |
3 |
10 |
Small-scale |
0.670 | High |
|
|
TN13B
Tumor necrosis factor ligand superfamily member 13B |
3 |
2 |
High-throughput |
0.667 | High |
|
|
KIF1B
Kinesin-like protein KIF1B |
1 |
12 |
High-throughput |
0.665 | High |
|
|
DYN2
Dynamin-2 |
1 |
2 |
High-throughput |
0.665 | High |
|
|
1433B
14-3-3 protein beta/alpha |
3 |
20 |
Small-scale |
0.657 | High |
|
|
MCRS1
Microspherule protein 1 |
1 |
0 |
Small-scale |
0.654 | High |
|
|
AURKA
Aurora kinase A |
1 |
16 |
High-throughput |
0.647 | High |
|
|
CDK4
Cyclin-dependent kinase 4 |
1 |
11 |
High-throughput |
0.647 | High |
|
|
FGFR4
Fibroblast growth factor receptor 4 |
1 |
20 |
High-throughput |
0.647 | High |
|
|
CCND2
G1/S-specific cyclin-D2 |
1 |
6 |
High-throughput |
0.647 | High |
|
|
CDK6
Cyclin-dependent kinase 6 |
1 |
16 |
High-throughput |
0.647 | High |
|
|
STK11
Serine/threonine-protein kinase STK11 |
1 |
17 |
High-throughput |
0.647 | High |
|
|
GLIS2
Zinc finger protein GLIS2 |
1 |
11 |
High-throughput |
0.647 | High |
|
|
ARRB2
Beta-arrestin-2 |
3 |
10 |
Small-scale |
0.646 | High |
|
|
1433T
14-3-3 protein theta |
3 |
20 |
Small-scale |
0.642 | High |
|
|
TRAF5
TNF receptor-associated factor 5 |
3 |
20 |
Small-scale |
0.640 | High |
|
|
CHIP
E3 ubiquitin-protein ligase CHIP |
3 |
15 |
Small-scale |
0.640 | High |
|
|
TNAP3
Tumor necrosis factor alpha-induced protein 3 |
2 |
14 |
Small-scale |
0.634 | High |
|
|
NEDD4
E3 ubiquitin-protein ligase NEDD4 |
2 |
20 |
Small-scale |
0.629 | High |
|
|
JIP3
C-Jun-amino-terminal kinase-interacting protein 3 |
2 |
20 |
Small-scale |
0.624 | High |
|
|
A4
Amyloid-beta precursor protein |
2 |
12 |
Small-scale |
0.621 | High |
|
|
CTRO
Citron Rho-interacting kinase |
1 |
18 |
High-throughput |
0.618 | High |
|
|
BIRC5
Baculoviral IAP repeat-containing protein 5 |
1 |
11 |
Small-scale |
0.618 | High |
|
|
CFLAR
CASP8 and FADD-like apoptosis regulator |
1 |
6 |
Small-scale |
0.618 | High |
|
|
HS90A
Heat shock protein HSP 90-alpha |
1 |
20 |
High-throughput |
0.618 | High |
|
|
HS90B
Heat shock protein HSP 90-beta |
1 |
20 |
High-throughput |
0.618 | High |
|
|
E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase |
1 |
19 |
Small-scale |
0.618 | High |
|
|
CANB1
Calcineurin subunit B type 1 |
1 |
12 |
Small-scale |
0.618 | High |
|
|
DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A |
1 |
20 |
Small-scale |
0.618 | High |
|
|
MK14
Mitogen-activated protein kinase 14 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
DUS19
Dual specificity protein phosphatase 19 |
1 |
6 |
Small-scale |
0.618 | High |
|
|
ALK
ALK tyrosine kinase receptor |
1 |
20 |
Small-scale |
0.618 | High |
|
|
ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622 |
1 |
1 |
Small-scale |
0.603 | High |
|
|
Q0VDC6
peptidylprolyl isomerase |
1 |
11 |
High-throughput |
0.594 | High |
|
|
PTN11
Tyrosine-protein phosphatase non-receptor type 11 |
1 |
7 |
Small-scale |
0.589 | High |
|
|
GSTM1
Glutathione S-transferase Mu 1 |
2 |
4 |
Small-scale |
0.584 | High |
|
|
TRAF1
TNF receptor-associated factor 1 |
2 |
17 |
Small-scale |
0.584 | High |
|
|
TRAF3
TNF receptor-associated factor 3 |
2 |
20 |
Small-scale |
0.584 | High |
|
|
PARK7
Parkinson disease protein 7 |
2 |
1 |
Small-scale |
0.584 | High |
|
|
FBW1B
F-box/WD repeat-containing protein 11 |
2 |
19 |
Small-scale |
0.584 | High |
|
|
SIAH1
E3 ubiquitin-protein ligase SIAH1 |
1 |
12 |
Small-scale |
0.578 | High |
|
|
GEMI5
Gem-associated protein 5 |
1 |
6 |
Small-scale |
0.578 | High |
|
|
ANM1
Protein arginine N-methyltransferase 1 |
1 |
2 |
Small-scale |
0.578 | High |
|
|
JAK1
Tyrosine-protein kinase JAK1 |
1 |
20 |
Small-scale |
0.575 | High |
|
|
TPD54
Tumor protein D54 |
1 |
2 |
Small-scale |
0.573 | High |
|
|
GA45B
Growth arrest and DNA damage-inducible protein GADD45 beta |
1 |
1 |
Small-scale |
0.561 | High |
|
|
PPP5
Serine/threonine-protein phosphatase 5 |
1 |
20 |
Small-scale |
0.561 | High |
|
|
SUMO1
Small ubiquitin-related modifier 1 |
1 |
6 |
Small-scale |
0.561 | High |
|
|
UBC9
SUMO-conjugating enzyme UBC9 |
1 |
18 |
Small-scale |
0.561 | High |
|
|
USP9X
Ubiquitin carboxyl-terminal hydrolase 9X |
1 |
16 |
Small-scale |
0.561 | High |
|
|
SMN
Survival motor neuron protein |
1 |
2 |
Small-scale |
0.543 | High |
|
|
DMD
Dystrophin |
1 |
20 |
High-throughput |
0.541 | High |
|
|
EP300
Histone acetyltransferase p300 |
1 |
18 |
High-throughput |
0.541 | High |
|
|
CBP
CREB-binding protein |
1 |
16 |
High-throughput |
0.541 | High |
|
|
TP8L1
Tumor necrosis factor alpha-induced protein 8-like protein 1 |
1 |
0 |
Small-scale |
0.537 | High |
|
|
EFMT3
EEF1A lysine methyltransferase 3 |
1 |
7 |
High-throughput |
0.536 | High |
|
|
NACC1
Nucleus accumbens-associated protein 1 |
1 |
16 |
High-throughput |
0.536 | High |
|
|
UBXN6
UBX domain-containing protein 6 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
RABE2
Rab GTPase-binding effector protein 2 |
1 |
20 |
High-throughput |
0.536 | High |
|
|
EGLN3
Prolyl hydroxylase EGLN3 |
1 |
6 |
High-throughput |
0.536 | High |
|
|
ATD3A
ATPase family AAA domain-containing protein 3A |
1 |
11 |
High-throughput |
0.536 | High |
|
|
STRAP
Serine-threonine kinase receptor-associated protein |
1 |
6 |
Small-scale |
0.536 | High |
|
|
THIOM
Thioredoxin, mitochondrial |
2 |
7 |
Small-scale |
0.533 | High |
|
|
TNR6
Tumor necrosis factor receptor superfamily member 6 |
1 |
4 |
Small-scale |
0.515 | High |
|
|
NH2L1
NHP2-like protein 1 |
1 |
2 |
High-throughput |
0.515 | High |
|
|
FBF1
Fas-binding factor 1 |
1 |
20 |
High-throughput |
0.515 | High |
|
|
HTRA2
Serine protease HTRA2, mitochondrial |
1 |
4 |
High-throughput |
0.515 | High |
|
|
CRYAA
Alpha-crystallin A chain |
1 |
8 |
High-throughput |
0.515 | High |
|
|
HSPB1
Heat shock protein beta-1 |
1 |
8 |
High-throughput |
0.515 | High |
|
|
IF2G
Eukaryotic translation initiation factor 2 subunit 3 |
1 |
12 |
High-throughput |
0.515 | High |
|
|
HD
Huntingtin |
1 |
8 |
High-throughput |
0.515 | High |
|
|
HSP72
Heat shock-related 70 kDa protein 2 |
1 |
20 |
High-throughput |
0.515 | High |
|
|
PRPS1
Ribose-phosphate pyrophosphokinase 1 |
1 |
1 |
High-throughput |
0.515 | High |
|
|
DYHC1
Cytoplasmic dynein 1 heavy chain 1 |
1 |
2 |
High-throughput |
0.515 | High |
|
|
KLK6
Kallikrein-6 |
1 |
5 |
High-throughput |
0.515 | High |
|
|
VPS29
Vacuolar protein sorting-associated protein 29 |
1 |
1 |
High-throughput |
0.515 | High |
|
|
HSF2B
Heat shock factor 2-binding protein |
1 |
0 |
High-throughput |
0.513 | High |
|
|
TERT
Telomerase reverse transcriptase |
1 |
1 |
High-throughput |
0.501 | High |
|
|
MBP
Myelin basic protein |
1 |
7 |
Small-scale |
0.501 | High |
|
|
MERL
Merlin |
1 |
16 |
High-throughput |
0.501 | High |
|
|
CDN2A
Cyclin-dependent kinase inhibitor 2A |
1 |
16 |
High-throughput |
0.501 | High |
|
|
TEAD2
Transcriptional enhancer factor TEF-4 |
1 |
2 |
High-throughput |
0.501 | High |
|
|
NED4L
E3 ubiquitin-protein ligase NEDD4-like |
1 |
20 |
High-throughput |
0.501 | High |
|
|
FZR1
Fizzy-related protein homolog |
1 |
6 |
High-throughput |
0.501 | High |
|
|
IF2B
Eukaryotic translation initiation factor 2 subunit 2 |
1 |
0 |
High-throughput |
0.493 | High |
|
|
GDAP1
Ganglioside-induced differentiation-associated protein 1 |
1 |
0 |
High-throughput |
0.493 | High |
|
|
SOCS3
Suppressor of cytokine signaling 3 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
AIFM1
Apoptosis-inducing factor 1, mitochondrial |
1 |
4 |
Small-scale |
0.479 | High |
|
|
G3P
Glyceraldehyde-3-phosphate dehydrogenase |
1 |
4 |
Small-scale |
0.479 | High |
|
|
GSTP1
Glutathione S-transferase P |
1 |
4 |
Small-scale |
0.479 | High |
|
|
ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A |
1 |
11 |
Small-scale |
0.479 | High |
|
|
PRS6A
26S proteasome regulatory subunit 6A |
1 |
11 |
Small-scale |
0.479 | High |
|
|
P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha |
1 |
12 |
Small-scale |
0.479 | High |
|
|
HSP74
Heat shock 70 kDa protein 4 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
GLRX1
Glutaredoxin-1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
PRS7
26S proteasome regulatory subunit 7 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
PRS6B
26S proteasome regulatory subunit 6B |
1 |
3 |
Small-scale |
0.479 | High |
|
|
SYQ
Glutamine--tRNA ligase |
1 |
3 |
Small-scale |
0.479 | High |
|
|
AAKG1
5'-AMP-activated protein kinase subunit gamma-1 |
1 |
7 |
Small-scale |
0.479 | High |
|
|
PRS4
26S proteasome regulatory subunit 4 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
PRS8
26S proteasome regulatory subunit 8 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
GNA12
Guanine nucleotide-binding protein subunit alpha-12 |
1 |
10 |
Small-scale |
0.479 | High |
|
|
KMT2A
Histone-lysine N-methyltransferase 2A |
1 |
13 |
Small-scale |
0.479 | High |
|
|
CUL3
Cullin-3 |
1 |
14 |
High-throughput |
0.479 | High |
|
|
CUL4A
Cullin-4A |
1 |
14 |
High-throughput |
0.479 | High |
|
|
GNA13
Guanine nucleotide-binding protein subunit alpha-13 |
1 |
9 |
Small-scale |
0.479 | High |
|
|
BRD3
Bromodomain-containing protein 3 |
1 |
11 |
High-throughput |
0.479 | High |
|
|
TPD53
Tumor protein D53 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
FIL1L
Filamin A-interacting protein 1-like |
1 |
20 |
High-throughput |
0.479 | High |
|
|
RBCC1
RB1-inducible coiled-coil protein 1 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
OTUB1
Ubiquitin thioesterase OTUB1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
TRAF4
TNF receptor-associated factor 4 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
TOLIP
Toll-interacting protein |
1 |
3 |
Small-scale |
0.479 | High |
|
|
UBP29
Ubiquitin carboxyl-terminal hydrolase 29 |
1 |
16 |
Small-scale |
0.479 | High |
|
|
XPO7
Exportin-7 |
1 |
17 |
High-throughput |
0.479 | High |
|
|
RN150
RING finger protein 150 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
FBW1A
F-box/WD repeat-containing protein 1A |
1 |
20 |
Small-scale |
0.479 | High |
|
|
GRN
Progranulin |
1 |
1 |
High-throughput |
0.470 | High |
|
|
LRP8
Low-density lipoprotein receptor-related protein 8 |
1 |
2 |
High-throughput |
0.470 | High |
|
|
IFT20
Intraflagellar transport protein 20 homolog |
1 |
0 |
Small-scale |
0.458 | High |
|
|
ABC3G
DNA dC->dU-editing enzyme APOBEC-3G |
1 |
0 |
Small-scale |
0.458 | High |
|
|
1433S
14-3-3 protein sigma |
1 |
20 |
Small-scale |
0.457 | High |
|
|
MYC
Myc proto-oncogene protein |
1 |
19 |
High-throughput |
0.445 | High |
|
|
TAU
Microtubule-associated protein tau |
1 |
20 |
Small-scale |
0.445 | High |
|
|
SYT1
Synaptotagmin-1 |
1 |
3 |
High-throughput |
0.445 | High |
|
|
TRAF7
E3 ubiquitin-protein ligase TRAF7 |
1 |
18 |
Small-scale |
0.437 | High |
|
|
PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial |
1 |
3 |
Small-scale |
0.437 | High |
|
|
TULP3
Tubby-related protein 3 |
1 |
0 |
High-throughput |
0.282 | High |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
