HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: ANKS6 (Q68DC2)
Ankyrin repeat and SAM domain-containing protein 6 (Ankyrin repeat domain-containing protein 14) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6)
Gene: ANKS6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 871
+	Hs
		350251 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ANKS6_HUMAN (1-871): 0: 568: 100.00
+	Dm
		1248518 Q962I2_DROME (4-181): 2.02e-61: 191: 50.82		Q8SWY2_DROME (9-844): 1.09e-121: 394: 16.03
+	Hs
		349000 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		KDIS_HUMAN (51-482): 1.86e-92: 322: 23.50
+	Hs
		350674 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		KDIS_HUMAN (51-482): 1.86e-92: 322: 23.50
+	Hs
		914450 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		KDIS_HUMAN (51-482): 1.86e-92: 322: 23.50
+	Hs
		349001 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		ANR50_HUMAN (3-363): 6.58e-73: 263: 20.78
+	Hs
		350675 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ANR50_HUMAN (3-363): 6.58e-73: 263: 20.78
+	Hs
		350083 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ANK2_HUMAN (3-298): 1.33e-63: 236: 23.31
+	Hs
		349253 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		ANK2_HUMAN (3-298): 1.33e-63: 236: 23.31
+	Hs
		350123 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ANK3_HUMAN (293-583): 6.94e-34: 143: 15.31
+	Dm
		65552 RALA_DROME (4-167): 1.35e-61: 191: 55.15		A8JNM5_DROME (266-576): 1.75e-34: 145: 13.85