HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 435
+	Hs
		350440 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		350710 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		AP3M1_HUMAN (1-434): 1.4e-123: 366: 24.66
+	Hs
		349214 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		AP3M2_HUMAN (1-434): 2.92e-119: 355: 24.89
+	Hs
		897974 RAP1B_HUMAN (1-165): 2.18e-63: 195: 57.49		AP3M1_HUMAN (1-434): 1.4e-123: 366: 24.66
+	Hs
		119701 RALA_HUMAN (4-168): 3.3e-59: 185: 54.22		AP4M1_HUMAN (1-434): 1.21e-116: 350: 26.88
+	Hs
		350403 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		STON2_HUMAN (146-433): 1.58e-62: 219: 22.85
+	Hs
		350747 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		STON1_HUMAN (149-408): 2.5e-58: 205: 21.75