HitPredict

Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck GO:0031397 - negative regulation of protein ubiquitination
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 475 Hs			1 400
+	Hs
		1063293 SART3_HUMAN (10-377): 4.33e-86: 285: 22.52		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1077515 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1054610 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1344522 PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1031475 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		516712 PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1063254 SART3_HUMAN (10-377): 4.33e-86: 285: 22.52		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1077447 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		SIR1_HUMAN (78-380): 5.06e-78: 257: 19.94
+	Hs
		1054434 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Mm
		857360 TIA1_MOUSE (253-475): 4.2e-36: 139: 15.70		SIR2_MOUSE (75-380): 2.24e-101: 307: 21.55