Protein: S39A2
Zinc transporter ZIP2 (6A1) (Eti-1) (Solute carrier family 39 member 2) (Zrt- and Irt-like protein 2) (ZIP-2) (hZIP2)

Gene: S39A2, SLC39A2
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q9NP94

Gene Ontology (top 5):
GO:0005385 - zinc ion transmembrane transporter activity
GO:0005886 - plasma membrane
GO:0006829 - zinc ion transport
GO:0030216 - keratinocyte differentiation
GO:0031410 - cytoplasmic vesicle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1446076

S39A9
Zinc transporter ZIP9

2

8

High-throughput

0.783

High

1446071

S39A2
Zinc transporter ZIP2

1

8

High-throughput

0.621

High

549891

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

1

High-throughput

0.606

High

642296

COMT
Catechol O-methyltransferase

2

8

High-throughput

0.606

High

668233

CXCR2
C-X-C chemokine receptor type 2

2

9

High-throughput

0.606

High

715965

AQP1
Aquaporin-1

2

3

High-throughput

0.606

High

722630

CTR1
High affinity cationic amino acid transporter 1

2

3

High-throughput

0.606

High

762165

CNR2
Cannabinoid receptor 2

2

20

High-throughput

0.606

High

762186

TRFR
Thyrotropin-releasing hormone receptor

2

6

High-throughput

0.606

High

870791

CXA8
Gap junction alpha-8 protein

2

12

High-throughput

0.606

High

1132582

FXYD3
FXYD domain-containing ion transport regulator 3

2

2

High-throughput

0.606

High

1310956

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

4

High-throughput

0.606

High

1351707

GP152
Probable G-protein coupled receptor 152

2

20

High-throughput

0.606

High

1358620

BT2A2
Butyrophilin subfamily 2 member A2

2

4

High-throughput

0.606

High

1400555

TM237
Transmembrane protein 237

2

1

High-throughput

0.606

High

1411150

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

4

High-throughput

0.606

High

1430274

FXYD6
FXYD domain-containing ion transport regulator 6

2

2

High-throughput

0.606

High

350324

LY66C
Lymphocyte antigen 6 complex locus protein G6c

2

0

High-throughput

0.580

High

1203802

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.580

High

1205541

M4A13
Membrane-spanning 4-domains subfamily A member 13

2

0

High-throughput

0.580

High

1254195

MFSD6
Major facilitator superfamily domain-containing protein 6

2

0

High-throughput

0.580

High

295709

UPK1B
Uroplakin-1b

2

8

High-throughput

0.553

High

883441

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

1

High-throughput

0.553

High

926848

VMAT1
Chromaffin granule amine transporter

2

1

High-throughput

0.553

High

1109055

AQP6
Aquaporin-6

2

3

High-throughput

0.553

High

1187570

AR13B
ADP-ribosylation factor-like protein 13B

2

7

High-throughput

0.553

High

1253272

LAAT1
Lysosomal amino acid transporter 1 homolog

2

1

High-throughput

0.553

High

1324431

TM86A
Lysoplasmalogenase TMEM86A

2

1

High-throughput

0.553

High

1359325

SSMM1
Serine-rich single-pass membrane protein 1

2

1

High-throughput

0.553

High

1369453

B2CL2
Bcl-2-like protein 2

2

1

High-throughput

0.553

High

1384356

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

4

High-throughput

0.553

High

1388806

YIPF6
Protein YIPF6

2

1

High-throughput

0.553

High

1394457

SC22A
Vesicle-trafficking protein SEC22a

2

4

High-throughput

0.553

High

1394917

SIAT2
Beta-galactoside alpha-2,6-sialyltransferase 2

2

4

High-throughput

0.553

High

1432037

TMM60
Transmembrane protein 60

2

1

High-throughput

0.553

High

1446074

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.553

High

193454

GPR42
G-protein coupled receptor 42

1

20

High-throughput

0.515

High

270481

FZD7
Frizzled-7

1

5

High-throughput

0.515

High

328744

VAMP5
Vesicle-associated membrane protein 5

1

2

High-throughput

0.515

High

718736

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

1

High-throughput

0.481

High

1135564

CLCA4
Calcium-activated chloride channel regulator 4

1

1

High-throughput

0.481

High

1363566

FAM3C
Protein FAM3C

1

11

High-throughput

0.470

High

178579

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

1

19

High-throughput

0.445

High

753846

MRP1
Multidrug resistance-associated protein 1

1

2

High-throughput

0.445

High

1105785

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

10

High-throughput

0.445

High

1217203

RIF1
Telomere-associated protein RIF1

1

3

High-throughput

0.445

High

1370780

RAB8B
Ras-related protein Rab-8B

1

6

High-throughput

0.445

High

1387071

COQ8B
Atypical kinase COQ8B, mitochondrial

1

2

High-throughput

0.445

High

1429431

T126A
Transmembrane protein 126A

1

2

High-throughput

0.445

High

341481

CDS2
Phosphatidate cytidylyltransferase 2

1

3

High-throughput

0.407

High

600517

ZNF3
Zinc finger protein 3

1

4

High-throughput

0.407

High

611366

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

12

High-throughput

0.407

High

749642

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

7

High-throughput

0.407

High

895297

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

8

High-throughput

0.407

High

1102910

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

2

High-throughput

0.407

High

1143681

NOMO1
BOS complex subunit NOMO1

1

1

High-throughput

0.407

High

1199840

AGK
Acylglycerol kinase, mitochondrial

1

1

High-throughput

0.407

High

1211801

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

1

High-throughput

0.407

High

1241166

LTMD1
LETM1 domain-containing protein 1

1

7

High-throughput

0.407

High

1270646

COX15
Heme A synthase COX15

1

2

High-throughput

0.407

High

1272027

ARMX2
Armadillo repeat-containing X-linked protein 2

1

5

High-throughput

0.407

High

1290325

S2542
Mitochondrial coenzyme A transporter SLC25A42

1

1

High-throughput

0.407

High

1339464

TOIP2
Torsin-1A-interacting protein 2

1

4

High-throughput

0.407

High

1356886

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

1

High-throughput

0.407

High

1365415

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

1

13

High-throughput

0.407

High

1365909

NU205
Nuclear pore complex protein Nup205

1

2

High-throughput

0.407

High

1381528

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

6

High-throughput

0.407

High

1384188

TM186
Transmembrane protein 186

1

2

High-throughput

0.407

High

1398966

F210A
Protein FAM210A

1

2

High-throughput

0.407

High

1410955

ODC
Mitochondrial 2-oxodicarboxylate carrier

1

1

High-throughput

0.407

High

1416296

SFXN3
Sideroflexin-3

1

1

High-throughput

0.407

High

1434699

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

2

High-throughput

0.407

High

1436099

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

5

High-throughput

0.407

High

1446073

HELLS
Lymphoid-specific helicase

1

2

High-throughput

0.407

High

1446075

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

1

High-throughput

0.407

High

1446078

CARF
CDKN2A-interacting protein

1

1

High-throughput

0.407

High

391756

STAT
Statherin

2

0

High-throughput

0.316

High

688419

PPLA
Phospholamban

2

0

High-throughput

0.316

High

712129

CO4A5

2

0

High-throughput

0.316

High

928878

LIPR1
Inactive pancreatic lipase-related protein 1

2

0

High-throughput

0.316

High

1249564

TM107
Transmembrane protein 107

2

0

High-throughput

0.316

High

1333273

T229B
Transmembrane protein 229B

2

0

High-throughput

0.316

High

1358718

SRALN
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN

2

0

High-throughput

0.316

High

1380430

TMM54
Transmembrane protein 54

2

0

High-throughput

0.316

High

1415007

EMC6
ER membrane protein complex subunit 6

2

0

High-throughput

0.316

High

1064031

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.268

Low

1312820

NRM
Nurim

1

0

High-throughput

0.268

Low

1446084

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

0

High-throughput

0.268

Low

1207626

F209A
Protein FAM209A

1

0

High-throughput

0.251

Low

1446079

TBA8
Tubulin alpha-8 chain

1

0

High-throughput

0.251

Low

325603

YIF1A
Protein YIF1A

1

0

High-throughput

0.232

Low

1146404

LRC41
Leucine-rich repeat-containing protein 41

1

0

High-throughput

0.232

Low

1149636

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.232

Low

1361679

ELYS
Protein ELYS

1

0

High-throughput

0.232

Low

1410321

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.232

Low

1446072

RM17
Large ribosomal subunit protein bL17m

1

0

High-throughput

0.232

Low

1446077

DMAC2
Distal membrane-arm assembly complex protein 2

1

0

High-throughput

0.232

Low

1446080

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.232

Low

1446081

AASS
Alpha-aminoadipic semialdehyde synthase, mitochondrial

1

0

High-throughput

0.232

Low

1446082

IPO11
Importin-11

1

0

High-throughput

0.232

Low

1446083

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025