HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: S12A2 (P55011)
Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2)
Gene: SLC12A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	30442766, 30639242, 30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1212
+	Hs
		349223 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		S12A2_HUMAN (1-1212): 0: 1285: 100.00
+	Hs
		348593 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		S12A2_HUMAN (1-1212): 0: 1285: 100.00
+	Hs
		873920 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		S12A2_HUMAN (1-1212): 0: 1285: 100.00
+	Hs
		873897 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		S12A2_HUMAN (1-1212): 0: 1285: 100.00
+	Hs
		873901 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		S12A2_HUMAN (1-1212): 0: 1285: 100.00
+	Hs
		349734 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		S12A4_HUMAN (167-1212): 0: 914: 23.71
+	Hs
		349008 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		S12A4_HUMAN (167-1212): 0: 914: 23.71
+	Hs
		1070458 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		S12A4_HUMAN (167-1212): 0: 914: 23.71
+	Hs
		350657 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		S12A6_HUMAN (148-1212): 0: 918: 22.65
+	Hs
		895310 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		S12A6_HUMAN (148-1212): 0: 918: 22.65
+	Hs
		350688 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		S12A4_HUMAN (167-1212): 0: 914: 23.71
+	Hs
		895321 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		S12A4_HUMAN (167-1212): 0: 914: 23.71
+	Hs
		349769 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		S12A7_HUMAN (163-1212): 0: 874: 22.62
+	Hs
		349035 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		S12A7_HUMAN (163-1212): 0: 874: 22.62
+	Hs
		1070484 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		S12A7_HUMAN (163-1212): 0: 874: 22.62
+	Hs
		350738 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		S12A7_HUMAN (163-1212): 0: 874: 22.62
+	Hs
		895338 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		S12A7_HUMAN (163-1212): 0: 874: 22.62
+	Mm
		1265035 RAB1B_MOUSE (4-187): 1.74e-73: 221: 31.96		S12A5_MOUSE (188-1212): 0: 851: 22.08
+	Hs
		350407 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		YLAT2_HUMAN (248-776): 1.22e-113: 366: 11.49
+	Hs
		895209 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		YLAT2_HUMAN (248-776): 1.22e-113: 366: 11.49